Natural and synthetic flavonoid derivatives as new potential tyrosinase inhibitors: A systematic review
Tyrosinase is a multifunctional glycosylated and copper-containing oxidase that is highly
prevalent in plants and animals and plays a pivotal role in catalyzing the two key steps of …
prevalent in plants and animals and plays a pivotal role in catalyzing the two key steps of …
Recent advances in the design and discovery of synthetic tyrosinase inhibitors
J Li, L Feng, L Liu, F Wang, L Ouyang, L Zhang… - European Journal of …, 2021 - Elsevier
Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting
catalytic step in the melanin biosynthesis and enzymatic browning. As a promising target …
catalytic step in the melanin biosynthesis and enzymatic browning. As a promising target …
Natural and bioinspired phenolic compounds as tyrosinase inhibitors for the treatment of skin hyperpigmentation: Recent advances
L Panzella, A Napolitano - Cosmetics, 2019 - mdpi.com
One of the most common approaches for control of skin pigmentation involves the inhibition
of tyrosinase, a copper-containing enzyme which catalyzes the key steps of melanogenesis …
of tyrosinase, a copper-containing enzyme which catalyzes the key steps of melanogenesis …
Tyrosinase inhibitors naturally present in plants and synthetic modifications of these natural products as anti-melanogenic agents: a review
Tyrosinase is a key enzyme target to design new chemical ligands against melanogenesis.
In the current review, different chemical derivatives are explored which have been used as …
In the current review, different chemical derivatives are explored which have been used as …
[HTML][HTML] Novel coumarin derivatives as potential tyrosinase inhibitors: synthesis, binding analysis and biological evaluation
L Lu, X Zhang, Y Kang, Z Xiong, K Zhang, X Xu… - Arabian Journal of …, 2023 - Elsevier
A novel series of thirty coumarin derivatives (4a∼ r, 5a∼ l) constituted by coumarin and
cinnamic acid/benzoic acid through oxime linkage were synthesized and evaluated for their …
cinnamic acid/benzoic acid through oxime linkage were synthesized and evaluated for their …
Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis
R Romagnoli, P Oliva, F Prencipe, S Manfredini… - European Journal of …, 2022 - Elsevier
A novel series of twenty-seven cinnamides constituted by cinnamic acid derivatives liked to
1-aryl piperazines were synthesized and evaluated for their potential inhibitory diphenolase …
1-aryl piperazines were synthesized and evaluated for their potential inhibitory diphenolase …
Molecular docking, synthesis, and tyrosinase inhibition activity of acetophenone amide: Potential inhibitor of melanogenesis
Tyrosinase and its related proteins are responsible for pigmentation disorders, and inhibiting
tyrosinase is an established strategy to treat hyperpigmentation. The carbonyl scaffolds can …
tyrosinase is an established strategy to treat hyperpigmentation. The carbonyl scaffolds can …
Anti-melanogenic potential of natural and synthetic substances: application in zebrafish model
AM Ferreira, AA de Souza, RCR Koga, IS Sena… - Molecules, 2023 - mdpi.com
Melanogenesis is a biosynthetic pathway for the formation of the pigment melanin in human
skin. A key enzyme in the process of pigmentation through melanin is tyrosinase, which …
skin. A key enzyme in the process of pigmentation through melanin is tyrosinase, which …
Synthesis and biological evaluation of benzimidazole derivatives as potential neuroprotective agents in an ethanol-induced rodent model
Alzheimer's disease (AD) is the most devastating and progressive neurodegenerative
disease in middle to elder aged people, which can be exacerbated by lifestyle factors …
disease in middle to elder aged people, which can be exacerbated by lifestyle factors …
Benzimidazole containing acetamide derivatives attenuate neuroinflammation and oxidative stress in ethanol-induced neurodegeneration
Oxidative stress-induced neuroinflammation is the prominent feature of neurodegenerative
disorders, and is characterized by a gradual decline of structure and function of neurons …
disorders, and is characterized by a gradual decline of structure and function of neurons …