The effect of a comprehensive typhoid conjugate vaccine campaign on antimicrobial prescribing in children in Harare, Zimbabwe: a mixed methods study
Background Vaccines prevent infections and could subsequently reduce antimicrobial use.
A 1-week mass vaccination campaign was done with Typbar-TCV (Bharat Biotech …
A 1-week mass vaccination campaign was done with Typbar-TCV (Bharat Biotech …
The role of tissue resident memory CD4 T cells in Salmonella infection: Implications for future vaccines
CE Depew, SJ McSorley - Vaccine, 2023 - Elsevier
Salmonella infections cause a wide range of intestinal and systemic disease that affects
global human health. While some vaccines are available, they do not mitigate the impact of …
global human health. While some vaccines are available, they do not mitigate the impact of …
The origins of haplotype 58 (H58) Salmonella enterica serovar Typhi
ME Carey, TN Thi Nguyen, DHN Tran… - Communications …, 2024 - nature.com
Antimicrobial resistance (AMR) poses a serious threat to the clinical management of typhoid
fever. AMR in Salmonella Typhi (S. Typhi) is commonly associated with the H58 lineage, a …
fever. AMR in Salmonella Typhi (S. Typhi) is commonly associated with the H58 lineage, a …
Assessment of vaccine herd protection in a cluster-randomised trial of Vi conjugate vaccine against typhoid fever: results of further analysis
Background A cluster-randomised trial of Vi-tetanus toxoid (Vi-TT) conjugate vaccine
conducted in urban Bangladeshi children found a high level of direct protection by Vi-TT but …
conducted in urban Bangladeshi children found a high level of direct protection by Vi-TT but …
Changes in monocyte subsets in volunteers who received an oral wild-type Salmonella Typhi challenge and reached typhoid diagnosis criteria
FR Toapanta, J Hu, KA Shirey, PJ Bernal… - Frontiers in …, 2024 - frontiersin.org
An oral Controlled Human Infection Model (CHIM) with wild-type S. Typhi was re-established
allowing us to explore the development of immunity. In this model,~ 55% of volunteers who …
allowing us to explore the development of immunity. In this model,~ 55% of volunteers who …
[PDF][PDF] Better diagnostic tools needed to distinguish typhoid from other causes of acute febrile illness
S Shakoor, S Dittrich - Bulletin of the World Health Organization, 2023 - iris.who.int
1. GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and
injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global …
injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global …
Typhoid conjugate vaccine effectiveness in Malawi: evaluation of a test-negative design using randomised, controlled clinical trial data
Y Liang, AJ Driscoll, PD Patel, S Datta… - The Lancet Global …, 2023 - thelancet.com
Background Typhoid conjugate vaccines are being introduced in low-income and middle-
income countries to prevent typhoid illness in children. Vaccine effectiveness studies assess …
income countries to prevent typhoid illness in children. Vaccine effectiveness studies assess …
Trends in antimicrobial resistance amongst Salmonella Typhi in Bangladesh: A 24-year retrospective observational study (1999–2022)
Background Rising antimicrobial resistance (AMR) in Salmonella Typhi restricts typhoid
treatment options, heightening concerns for pan-oral drug-resistant outbreaks. However …
treatment options, heightening concerns for pan-oral drug-resistant outbreaks. However …
Intranasal immunization of mice with chimera of Salmonella Typhi protein elicits protective intestinal immunity
S Chakraborty, P Dutta, A Pal, S Chakraborty, G Banik… - npj Vaccines, 2024 - nature.com
Abstract Development of safe, highly effective and affordable enteric fever vaccines is a
global health priority. Live, oral typhoid vaccines induce strong mucosal immunity and long …
global health priority. Live, oral typhoid vaccines induce strong mucosal immunity and long …
[HTML][HTML] Clinical, phenotypic, and genotypic characteristics of ESBL-producing Salmonella enterica bloodstream infections from Qatar
Abstract Background Resistant Salmonella infections are a major global public health
challenge particularly for multidrug-resistant (MDR) isolates manifesting as bloodstream …
challenge particularly for multidrug-resistant (MDR) isolates manifesting as bloodstream …