Multiple sclerosis is a chronic, demyelinating disease of the CNS. Cognitive impairment is a
sometimes neglected, yet common, sign and symptom with a profound effect on instrumental …

Background: Analysis of the human connectome using functional magnetic resonance
imaging (fMRI) started in the mid-1990s and attracted increasing attention in attempts to …

Cognitive and motor performance measures are commonly employed in multiple sclerosis
(MS) research, particularly when the purpose is to determine the efficacy of treatment. The …

Cognitive impairment is increasingly recognized to be a core feature of multiple sclerosis
(MS), with important implications for the everyday life of individuals with MS and for disease …

Multiple sclerosis (MS) is a chronic disease with an inflammatory and neurodegenerative
pathology. Axonal loss and neurodegeneration occurs early in the disease course and may …

Background: Information processing speed (IPS) is a prevalent cognitive impairment in
multiple sclerosis (MS). Objectives: This review aims to summarize the methods applied to …

Objective: This study investigates whether changes in functional connectivity, diffusivity, and
volume of the thalamus can explain different severities of cognitive impairment in multiple …

Cognitive impairment affects 40–60% of patients with multiple sclerosis. It may be present
early in the course of the disease and has an impact on a patient's employability, social …

Network science provides powerful access to essential organizational principles of the
human brain. It has been applied in combination with graph theory to characterize brain …

Multiple sclerosis (MS) produces demyelination and degeneration in both gray and white
matter. Both cortical and deep gray matter injury is observed during the course of MS …