Extracellular matrix mechanobiology in cancer cell migration
The extracellular matrix (ECM) is pivotal in modulating tumor progression. Besides
chemically stimulating tumor cells, it also offers physical support that orchestrates the …
chemically stimulating tumor cells, it also offers physical support that orchestrates the …
[HTML][HTML] Bubble nucleation and dynamics in acoustic droplet vaporization: a review of concepts, applications, and new directions
The development of phase-shift droplets has broadened the scope of ultrasound-based
biomedical applications. When subjected to sufficient acoustic pressures, the …
biomedical applications. When subjected to sufficient acoustic pressures, the …
Ultrasound Mediated Polymerization for Cell Delivery, Drug Delivery, and 3D Printing
Safe and accurate in situ delivery of biocompatible materials is a fundamental requirement
for many biomedical applications. These include sustained and local drug release …
for many biomedical applications. These include sustained and local drug release …
A biomimetic renal fibrosis progression model on-chip evaluates anti-fibrotic effects longitudinally in a dynamic fibrogenic niche
D Wu, J Wu, H Liu, S Shi, L Wang, Y Huang, X Yu… - Lab on a Chip, 2023 - pubs.rsc.org
Although renal fibrosis can advance chronic kidney disease and progressively lead to end-
stage renal failure, no effective anti-fibrotic drugs have been clinically approved. To aid drug …
stage renal failure, no effective anti-fibrotic drugs have been clinically approved. To aid drug …
Ultrasound-induced drug release from stimuli-responsive hydrogels
TJ Yeingst, JH Arrizabalaga, DJ Hayes - Gels, 2022 - mdpi.com
Stimuli-responsive hydrogel drug delivery systems are designed to release a payload when
prompted by an external stimulus. These platforms have become prominent in the field of …
prompted by an external stimulus. These platforms have become prominent in the field of …
[HTML][HTML] Multi-time scale characterization of acoustic droplet vaporization and payload release of phase-shift emulsions using high-speed microscopy
Acoustic droplet vaporization (ADV) is the phase-transitioning of perfluorocarbon emulsions,
termed phase-shift emulsions, into bubbles using focused ultrasound. ADV has been utilized …
termed phase-shift emulsions, into bubbles using focused ultrasound. ADV has been utilized …
[HTML][HTML] Ultra-high-speed dynamics of acoustic droplet vaporization in soft biomaterials: Effects of viscoelasticity, frequency, and bulk boiling point
Phase-shift droplets are a highly adaptable platform for biomedical applications of
ultrasound. The spatiotemporal response of phase-shift droplets to focused ultrasound …
ultrasound. The spatiotemporal response of phase-shift droplets to focused ultrasound …
Micropatterning of acoustic droplet vaporization in acoustically-responsive scaffolds using extrusion-based bioprinting
Acoustically-responsive scaffolds (ARSs) are composite hydrogels that respond to
ultrasound in an on-demand, spatiotemporally-controlled manner due to the presence of a …
ultrasound in an on-demand, spatiotemporally-controlled manner due to the presence of a …
Ultrasound-assisted tissue engineering
Combining cells, biomaterials and bioactive factors with biophysical cues to engineer cell
and tissue constructs can address various applications, such as regenerative and …
and tissue constructs can address various applications, such as regenerative and …
Ultrasound‐induced mechanical compaction in acoustically responsive scaffolds promotes spatiotemporally modulated signaling in triple negative breast cancer
BA Humphries, M Aliabouzar… - Advanced …, 2022 - Wiley Online Library
Cancer cells continually sense and respond to mechanical cues from the extracellular matrix
(ECM). Interaction with the ECM can alter intracellular signaling cascades, leading to …
(ECM). Interaction with the ECM can alter intracellular signaling cascades, leading to …