Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy
LA Smith, F Azariah, VTC Lavender… - Cochrane Database …, 2015 - cochranelibrary.com
Background Cannabis has a long history of medicinal use. Cannabis‐based medications
(cannabinoids) are based on its active element, delta‐9‐tetrahydrocannabinol (THC), and …
(cannabinoids) are based on its active element, delta‐9‐tetrahydrocannabinol (THC), and …
Prognostic factors for chemotherapy induced nausea and vomiting
D Warr - European journal of pharmacology, 2014 - Elsevier
Purpose: to review the topic of prognostic factors for chemotherapy-induced nausea and
vomiting. Multiple patient factors such as age, gender and alcohol intake have been found …
vomiting. Multiple patient factors such as age, gender and alcohol intake have been found …
[HTML][HTML] Antiemetic activity of trans-ferulic acid possibly through muscarinic receptors interaction pathway: In vivo and in silico study
Current study was conducted to assess the effectiveness of the polyphenol trans-ferulic acid
(TFA) as an antiemetic agent using in vivo and in silico methods. To evaluate this, we …
(TFA) as an antiemetic agent using in vivo and in silico methods. To evaluate this, we …
Modulatory effects of phytol on the antiemetic property of domperidone, possibly through the D2 receptor interaction pathway: in vivo and in silico studies
The current study is designed to evaluate the antiemetic effect of the diterpenoid phytol
(PHY) using in vivo and in silico studies. For this, emesis was induced in 4-day-old chicks by …
(PHY) using in vivo and in silico studies. For this, emesis was induced in 4-day-old chicks by …
[HTML][HTML] Cryo-EM structure of 5-HT3A receptor in its resting conformation
Abstract Serotonin receptors (5-HT3AR) directly regulate gut movement, and drugs that
inhibit 5-HT3AR function are used to control emetic reflexes associated with gastrointestinal …
inhibit 5-HT3AR function are used to control emetic reflexes associated with gastrointestinal …
[HTML][HTML] Assessment of quercetin antiemetic properties: In vivo and in silico investigations on receptor binding affinity and synergistic effects
Quercetin (QUA), a flavonoid compound, is ubiquitously found in plants and has
demonstrated a diverse range of biological activities. The primary objective of the current …
demonstrated a diverse range of biological activities. The primary objective of the current …
Nausea still the poor relation in antiemetic therapy? The impact on cancer patients' quality of life and psychological adjustment of nausea, vomiting and appetite loss …
C Pirri, E Bayliss, J Trotter, IN Olver, P Katris… - Supportive care in …, 2013 - Springer
Purpose Despite significant antiemetic advances, almost 50% of treated cancer patients still
experience nausea and vomiting (N&V). The goal of antiemetic therapy—complete …
experience nausea and vomiting (N&V). The goal of antiemetic therapy—complete …
Nanotechnology based blended chitosan-pectin hybrid for safe and efficient consolidative antiemetic and neuro-protective effect of meclizine hydrochloride in …
AH Salama, H Elmotasem, AAA Salama - International Journal of …, 2020 - Elsevier
The aim of this study was to formulate an easily-administered, safe and effective dosage
form loaded with meclizine for treatment of chemotherapy-induced nausea and vomiting …
form loaded with meclizine for treatment of chemotherapy-induced nausea and vomiting …
Neurochemical mechanisms and pharmacologic strategies in managing nausea and vomiting related to cyclic vomiting syndrome and other gastrointestinal disorders
M Bashashati, RW McCallum - European journal of pharmacology, 2014 - Elsevier
Nausea and vomiting are common gastrointestinal complaints which could be triggered by
stimuli in both the peripheral and central nervous systems. They may be considered as …
stimuli in both the peripheral and central nervous systems. They may be considered as …
Efficacy of palonosetron in postoperative nausea and vomiting (PONV)—a meta-analysis
PM Singh, A Borle, D Gouda, JK Makkar… - Journal of clinical …, 2016 - Elsevier
Introduction Palonosetron is a second-generation 5-HT3 receptor antagonist with proposed
higher efficacy and sustained action for prophylaxis of postoperative nausea and vomiting …
higher efficacy and sustained action for prophylaxis of postoperative nausea and vomiting …