K-edge subtraction synchrotron X-ray imaging in bio-medical research

W Thomlinson, H Elleaume, L Porra, P Suortti - Physica Medica, 2018 - Elsevier
High contrast in X-ray medical imaging, while maintaining acceptable radiation dose levels
to the patient, has long been a goal. One of the most promising methods is that of K-edge …

Coherence-enhanced synchrotron radiology: simple theory and practical applications

Y Hwu, WL Tsai, A Groso… - Journal of Physics D …, 2002 - iopscience.iop.org
The advanced characteristics of synchrotron x-ray sources make it possible to implement
radiology with powerful and innovative approaches. We review in simple terms the …

Photoactivation of gold nanoparticles for glioma treatment

L Bobyk, M Edouard, P Deman, M Vautrin… - … , Biology and Medicine, 2013 - Elsevier
Radiosensitization efficacy of gold nanoparticles (AuNPs) with low energy radiations (88
keV) was evaluated in vitro and in vivo on rats bearing glioma. In vitro, a significant dose …

Synchrotron radiation-based experimental determination of the optimal energy for cell radiotoxicity enhancement following photoelectric effect on stable iodinated …

S Corde, A Joubert, JF Adam, AM Charvet… - British journal of …, 2004 - nature.com
This study was designed to experimentally evaluate the optimal X-ray energy for increasing
the radiation energy absorbed in tumours loaded with iodinated compounds, using the …

Synchrotron microbeam radiation therapy for rat brain tumor palliation—influence of the microbeam width at constant valley dose

R Serduc, A Bouchet, E Bräuer-Krisch… - Physics in Medicine …, 2009 - iopscience.iop.org
To analyze the effects of the microbeam width (25, 50 and 75 µm) on the survival of 9L
gliosarcoma tumor-bearing rats and on toxicity in normal tissues in normal rats after …

High-precision radiosurgical dose delivery by interlaced microbeam arrays of high-flux low-energy synchrotron X-rays

R Serduc, E Bräuer-Krisch, EA Siegbahn, A Bouchet… - PLoS one, 2010 - journals.plos.org
Microbeam Radiation Therapy (MRT) is a preclinical form of radiosurgery dedicated to brain
tumor treatment. It uses micrometer-wide synchrotron-generated X-ray beams on the basis …

MOSFET dosimetry for microbeam radiation therapy at the European Synchrotron Radiation Facility

E Bräuer‐Krisch, A Bravin, M Lerch… - Medical …, 2003 - Wiley Online Library
Preclinical experiments are carried out with∼ 20–30 μm wide,∼ 10 mm high parallel
microbeams of hard, broad‐“white”‐spectrum x rays (∼ 50–600 keV) to investigate …

Synergy of gene-mediated immunoprophylaxis and microbeam radiation therapy for advanced intracerebral rat 9L gliosarcomas

HM Smilowitz, H Blattmann, E Bräuer-Krisch… - Journal of neuro …, 2006 - Springer
Purpose Microbeam radiation therapy (MRT), a novel experimental radiosurgery that largely
spares the developing CNS and other normal tissues, is tolerated well by developing …

Radiosurgical palliation of aggressive murine SCCVII squamous cell carcinomas using synchrotron-generated X-ray microbeams

M Miura, H Blattmann, E Brauer-Krisch… - The British Journal of …, 2006 - academic.oup.com
Microbeam radiosurgery (MBRS), also referred to as microbeam radiation therapy (MRT),
was tested at the European Synchrotron Radiation Facility (ESRF). The left tibiofibular thigh …

New irradiation geometry for microbeam radiation therapy

E Bräuer-Krisch, H Requardt, P Regnard… - Physics in Medicine …, 2005 - iopscience.iop.org
Microbeam radiation therapy (MRT) has the potential to treat infantile brain tumours when
other kinds of radiotherapy would be excessively toxic to the developing normal brain. MRT …