Evidence from clinical, preclinical, and post-mortem studies supports the
inflammatory/immune hypothesis of schizophrenia pathogenesis. Less evident is the link …

Ischemic stroke is a leading cause of morbidity and death, with the outcome largely
determined by the amount of hypoxia-related neuronal death in the affected brain regions …

There are virtually no clinically available neuroprotective drugs for the treatment of acute
and chronic neurological disorders, hence there is an urgent need for the development of …

Schizophrenia is a worldwide mental illness characterized by alterations at dopaminergic
and glutamatergic synapses resulting in global dysconnectivity within and between brain …

Using cortical neuronal cultures and glutamic acid excitotoxicity and oxygen-glucose
deprivation (OGD) stroke models, we demonstrated that poly-arginine and arginine-rich cell …

Several recent studies have demonstrated that TAT and other arginine-rich cell penetrating
peptides (CPPs) have intrinsic neuroprotective properties in their own right. Examples, we …

Neurodegenerative diseases, including Alzheimer̕ s disease (AD), Parkinson̕ s disease
(PD), Huntington̕ s disease (HD), and Amyotrophic Lateral Sclerosis (ALS) require special …

Efficient cargo uptake is essential for cell-penetrating peptide (CPP) therapeutics, which
deliver widely diverse cargoes by exploiting natural cell processes to penetrate the cell's …

Cell-penetrating peptides (CPPs) are small peptides (typically 5–25 amino acids), which are
used to facilitate the delivery of normally non-permeable cargos such as other peptides …

Stroke is the second leading cause of death globally and represents a major cause of
devastating long-term disability. Despite sustained efforts to develop clinically effective …