The relative contribution of founder effects and natural selection to the observed distribution
of human blood groups has been debated since blood group frequencies were shown to …

The ABO blood group system revisited: a review and update Blog English EnglishGerman
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Anti‐D (‐RH 1) of the Rh blood group system is clinically important as it causes haemolytic
transfusion reactions and haemolytic disease of the fetus and newborn. Although most …

In 2014, the College of American Pathologists (CAP) Transfusion Medicine Resource
Committee (TMRC) reported the results of a survey of more than 3100 laboratories …

To date, 33 human platelet alloantigens (HPA s) have been identified on six functionally
important platelet glycoprotein (GP) complexes and have been implicated in alloimmune …

Over the past 20 years the molecular bases of almost all the major blood group antigens
have been determined. This research has enabled development of DNA-based methods for …

Background Matching donor red blood cells based on recipient antigens prevents
alloimmunisation. Knowledge about the immunogenicity of red-blood-cell antigens can help …

Over 300 blood group specificities on red cells have been identified, many of which are
polymorphic. The molecular mechanisms responsible for these polymorphisms are diverse …

Blood group antigens, present on the cell membrane of red blood cells and platelets, can be
defined either serologically or predicted based on the genotypes of genes encoding for …

The molecular background of blood group antigen expression of the major clinically
significant blood group antigens has been largely accomplished. Despite this large body of …