Nickel enzymes, present in archaea, bacteria, plants, and primitive eukaryotes are divided
into redox and nonredox enzymes and play key functions in diverse metabolic processes …

Urease is a kind of enzyme which could be found in various bacteria, fungi, plants, and
algae, which can quickly catalyze the hydrolysis of urea into ammonia and carbon dioxide …

A new series of N-thioacylated ciprofloxacin 3a–n were designed and synthesized based on
Willgerodt–Kindler reaction. The results of in vitro urease inhibitory assay indicated that …

Enzyme-induced calcium carbonate precipitation (EICP) techniques are used in several
disciplines and for a wide range of applications. In the oil and gas industry, EICP is a …

Screening of 25 analogs of Ebselen, diversified at the N-aromatic residue, led to the
identification of the most potent inhibitors of Sporosarcina pasteurii urease reported to date …

Infection and blockage of indwelling urinary catheters is significant owing to its high
incidence rate and severe medical consequences. Bacterial enzymes are employed as …

Urease, an enzyme that catalyzes the hydrolysis of urea, is a virulence factor of various
pathogenic bacteria. In particular, Helicobacter pylori, that colonizes the digestive tract and …

Urea cocrystal materials have recently emerged as high nitrogen (N) content fertilizers with
low solubility capable of minimizing N loss and improving their use efficiency. However, their …

In this study, a new class of bifunctional inhibitors of bacterial ureases, important molecular
targets for antimicrobial therapies, was developed. The structures of the inhibitors consist of …

Urease catalyzes the hydrolysis of urea to form ammonia and carbamate, inducing an
overall pH increase that affects both human health and agriculture. Inhibition, mutagenesis …