440 RASKIN discovered that the leaves and bark of the willow tree cured aches and fevers.
In the 4th century Be Hippocrates gave willow leaves to women to chew as a pain reliever …

Traditionally, the analgesic action of nonsteroidal anti-inflammatory drugs (NSAIDs) has
been explained on the basis of their inhibition of the enzymes that synthesise …

The second near‐infrared (NIR‐II) fluorescent imaging shows great potential for deep tissue
analysis at high resolution in living body owing to low background autofluorescence and …

The transcription factor nuclear factor-κB (NF-κB) is critical for the inducible expression of
multiple cellular and viral genes involved in inflammation and infection including interleukin …

Several studies have demonstrated unequivocally that certain nonsteroidal anti‐
inflammatory drugs (NSAIDs) such as sodium salicylate, sulindac, ibuprofen, and …

In mammalian species and in the oldest of multicellular animal forms, NSAIDs inhibit cell
activation, apparently in the absence of effects on PG biosynthesis. Thus, an alternative …

Nitric oxide provokes vasodilation and inhibits platelet aggregation. We examined the effect
of nitric oxide on superoxide anion production by three sources: activated intact neutrophils …

First published in 1990: The Endothelium: Modulator of Cardiovascular Function takes a
comprehensive look at the role of the endothelium in cardiovascular control in health and …

Injection of mineral oils such as pristane into the peritoneal cavities of BALB/c mice results in
a chronic peritonitis associated with high tissue levels of interleukin 6 (IL-6). Here we show …

Non-steroidal anti-inflammatory drugs have a direct action on spinal nociceptive processing
in vivo with a relative order of potency which correlates with their capacity as inhibitors of …