Being the most common musculoskeletal progressive condition, osteoarthritis is an
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …

Osteoarthritis (OA) is a complicated degenerative disease that affects whole joint tissue.
Currently, apart from surgical approaches to treat late stage OA, effective treatments to …

Osteoarthritis (OA) is a joint pathology characterized by progressive cartilage degradation.
Medical care is mainly based on alleviating pain symptoms. Compelling studies report the …

The transforming growth factor beta (TGF‐β) family forms a group of three isoforms, TGF‐β1,
TGF‐β2, and TGF‐β3, with their structure formed by interrelated dimeric polypeptide chains …

Articular cartilage shows limited self-healing ability owing to its low cellularity and
avascularity. Untreated cartilage defects display an increased propensity to degenerate …

The regeneration of complex tissues and organs remains a major clinical challenge. With a
view towards bioprinting such tissues, we developed a new class of pore-forming bioink to …

Osteoarthritis (OA) is a degenerative whole joint disease, for which no preventative or
therapeutic biological interventions are available. This is likely due to the fact that OA …

Members of the TGF-β superfamily are important regulators of chondrocyte function. Sox9, a
key transcriptional regulator of chondrogenesis, is required for TGF-β-mediated regulation of …

Osteoarthritis (OA) affects a large number of the population, and its incidence is showing a
growing trend with the increasing life span. OA is the most prevalent joint condition …

Controlling the phenotype of mesenchymal stem cells (MSCs) through the delivery of
regulatory genes is a promising strategy in tissue engineering (TE). Essential to effective …