Objectives The objective of the study is to present the Grading of Recommendations
Assessment, Development, and Evaluation (GRADE) conceptual approach to the …

A few decades ago, drug discovery and development were limited to a bunch of medicinal
chemists working in a lab with enormous amount of testing, validations, and synthetic …

Objective To find out which interventions enhance pain self-efficacy in people with chronic
musculoskeletal pain and to evaluate the reporting of interventions designed to enhance …

Two-thirds of individuals experience adversity during childhood such as neglect, abuse or
highly-stressful events. Early-life adversity (ELA) increases the life-long risk of developing …

Objectives The public, policy makers, and science communities are subject to many false,
uninformed, overly optimistic, premature, or simply ridiculous health claims. The coronavirus …

Abstract Background The World Health Organization is coordinating an international project
aimed at systematically reviewing the evidence regarding the association between …

Biodegradable metals hold promises for bone fracture repair. Their clinical translation
requires pre-clinical evaluations including animal studies, which demonstrate the safety and …

An unmet but urgent medical need is the development of myelin repair promoting therapies
for Multiple Sclerosis (MS). Many such therapies have been pre-clinically tested using …

Background: Physiological responses related to manual therapy (MT) treatment have been
investigated over decades using various animal models. However, these studies have not …

Background The carcinogenicity of radiofrequency electromagnetic fields (RF EMF) has
been evaluated by the International Agency for Research on Cancer (IARC) in 2011. Based …