Systematic review of polygenic gene–environment interaction in tobacco, alcohol, and cannabis use
Studies testing the effect of single genetic variants on substance use have had modest
success. This paper reviewed 39 studies using polygenic measures to test interaction with …
success. This paper reviewed 39 studies using polygenic measures to test interaction with …
A genome-wide association study of bitter and sweet beverage consumption
VW Zhong, A Kuang, RD Danning, P Kraft… - Human molecular …, 2019 - academic.oup.com
Except for drinking water, most beverages taste bitter or sweet. Taste perception and
preferences are heritable and determinants of beverage choice and consumption …
preferences are heritable and determinants of beverage choice and consumption …
[HTML][HTML] Predicting risk for Alcohol Use Disorder using longitudinal data with multimodal biomarkers and family history: a machine learning study
Predictive models have succeeded in distinguishing between individuals with Alcohol use
Disorder (AUD) and controls. However, predictive models identifying who is prone to …
Disorder (AUD) and controls. However, predictive models identifying who is prone to …
Predicting alcohol use disorder remission: a longitudinal multimodal multi-featured machine learning approach
Predictive models for recovering from alcohol use disorder (AUD) and identifying related
predisposition biomarkers can have a tremendous impact on addiction treatment outcomes …
predisposition biomarkers can have a tremendous impact on addiction treatment outcomes …
Alcohol consumption is associated with widespread changes in blood DNA methylation: analysis of cross‐sectional and longitudinal data
DNA methylation may be one of the mechanisms by which alcohol consumption is
associated with the risk of disease. We conducted a large‐scale, cross‐sectional, genome …
associated with the risk of disease. We conducted a large‐scale, cross‐sectional, genome …
Genetic associations between alcohol phenotypes and life satisfaction: a genomic structural equation modelling approach
Alcohol use (ie, quantity, frequency) and alcohol use disorder (AUD) are common,
associated with adverse outcomes, and genetically-influenced. Genome-wide association …
associated with adverse outcomes, and genetically-influenced. Genome-wide association …
Age varying polygenic effects on alcohol use in African Americans and European Americans from adolescence to adulthood
Genetic effects on alcohol use can vary over time but are often examined using longitudinal
models that predict a distal outcome at a single time point. The vast majority of these studies …
models that predict a distal outcome at a single time point. The vast majority of these studies …
A statistical genetic investigation of psychiatric resilience
Background: Although trauma exposure (TE) is a transdiagnostic risk factor for many
psychiatric disorders, not everyone who experiences TE develops a psychiatric disorder …
psychiatric disorders, not everyone who experiences TE develops a psychiatric disorder …
Polygenic contributions to alcohol use and alcohol use disorders across population-based and clinically ascertained samples
Background Studies suggest that alcohol consumption and alcohol use disorders have
distinct genetic backgrounds. Methods We examined whether polygenic risk scores (PRS) …
distinct genetic backgrounds. Methods We examined whether polygenic risk scores (PRS) …
Associations between polygenic risk for tobacco and alcohol use and liability to tobacco and alcohol use, and psychiatric disorders in an independent sample of …
Background Substance use, substance use disorders (SUDs), and psychiatric disorders
commonly co-occur. Genetic risk common to these complex traits is an important …
commonly co-occur. Genetic risk common to these complex traits is an important …