Neutrophilic polymorphonuclear leukocytes (neutrophils) are highly specialized for their
primary function, the phagocytosis and destruction of microorganisms. When coated with …

This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …

ContextMyeloperoxidase (MPO), a leukocyte enzyme that promotes oxidation of lipoproteins
in atheroma, has been proposed as a possible mediator of atherosclerosis. ObjectiveTo …

BACKGROUNDS: Many lines of evidence suggest that oxidized low-density lipoprotein
(LDL) is implicated in the pathogenesis of atherosclerotic vascular diseases. This review …

Atherosclerosis is a chronic inflammatory process where oxidative damage within the artery
wall is implicated in the pathogenesis of the disease. Mononuclear phagocytes, an …

The literature relating lipid and lipoprotein oxidation to atherosclerosis has expanded
enormously in recent years. Papers on the “oxidative modification hypothesis” of …

Inflammation leads to changes in lipid metabolism aimed at decreasing the toxicity of a
variety of harmful agents and tissue repair by redistributing nutrients to cells involved in host …

Initiation of lipid peroxidation and the formation of bioactive eicosanoids are pivotal
processes in inflammation and atherosclerosis. Currently, lipoxygenases, cyclooxygenases …

Paraoxonases PON1 and PON3, which are both associated in serum with HDL, protect the
serum lipids from oxidation, probably as a result of their ability to hydrolyze specific oxidized …