In addition to fatty acids, glucose and lactate are important myocardial substrates under
physiologic and stress conditions. They are metabolized to pyruvate, which enters …

1. The yield of mitochondria isolated from perfused hearts subjected to 30 min ischaemia
followed by 15 min reperfusion was significantly less than that for control hearts, and this …

Publisher Summary This chapter discusses the relations between the mitochondrial space
and the cytoplasmic space. It has been widely assumed that the cytoplasmic space can be …

BIOCHEMICAL OXIDATION-REDUCTION, or redox, reactions, which involve electron
transfer, are as ubiquit, ous and of as much quantitative significance to the body economy as …

Arteriovenous differences (AV) of all naturally occurring amino acids, lactate, and oxygen
were measured simultaneously with coronary sinus blood flow (CSBF) in 8 normal subjects …

1. In the isolated perfused rat heart, the contractile activity and the oxygen uptake were
varied by altering the aortic perfusion pressure, or by the atrial perfusion technique ('working …

MATERIALS AND METHODS L-Alanine dehydrogenase(EC 1.4. 1.1.), L-glutamate
dehydrogenase (EC 1.4. 1.3.), and beef heart L-lactate dehydrogenase(EC 1.1. 1.27). as a …

1. Time courses for the uptake of L-lactate, D-lactate and pyruvate into isolated cardiac
ventricular myocytes from guinea pig were determined at 11 degrees C or 0 degrees C (for …

The value of measurements of lactate in coronary venous blood as a sign of myocardial
anaerobiosis is reassessed. Lactate was measured after coronary arterial ligation in dogs in …

Cardiac contractile function is adenosine-5'-triphosphate (ATP)-intensive, and the
myocardium's high demand for oxygen and energy substrates leaves it acutely vulnerable to …