Thiazoles, their benzofused systems, and thiazolidinone derivatives: versatile and promising tools to combat antibiotic resistance
S Cascioferro, B Parrino, D Carbone… - Journal of medicinal …, 2020 - ACS Publications
Thiazoles, their benzofused systems, and thiazolidinone derivatives are widely recognized
as nuclei of great value for obtaining molecules with various biological activities, including …
as nuclei of great value for obtaining molecules with various biological activities, including …
Synthesis of antimicrobial benzimidazole–pyrazole compounds and their biological activities
M Marinescu - Antibiotics, 2021 - mdpi.com
The synthesis of new compounds with antimicrobial and antiviral properties is a central
objective today in the context of the COVID-19 pandemic. Benzimidazole and pyrazole …
objective today in the context of the COVID-19 pandemic. Benzimidazole and pyrazole …
A novel of quinoxaline derivatives tagged with pyrrolidinyl scaffold as a new class of antimicrobial agents: Design, synthesis, antimicrobial activity, and molecular …
MM Abdelgalil, YA Ammar, GAME Ali, AK Ali… - Journal of Molecular …, 2023 - Elsevier
Globally, infectious diseases are becoming harder to treat due to antibiotic resistance, which
has reached high levels. Additionally, developing new therapeutic options to combat the …
has reached high levels. Additionally, developing new therapeutic options to combat the …
[HTML][HTML] In vitro antimicrobial evaluation, single-point resistance study, and radiosterilization of novel pyrazole incorporating thiazol-4-one/thiophene derivatives as …
HA Mohamed, YA Ammar, GAM Elhagali, HA Eyada… - ACS …, 2022 - ncbi.nlm.nih.gov
A series of thiazol-4-one/thiophene-bearing pyrazole derivatives as pharmacologically
attractive cores were initially synthesized using a hybridization approach. All structures were …
attractive cores were initially synthesized using a hybridization approach. All structures were …
In Vitro Antimicrobial Evaluation, Single-Point Resistance Study, and Radiosterilization of Novel Pyrazole Incorporating Thiazol-4-one/Thiophene Derivatives as Dual …
H Ali Mohamed, YA Ammar, G AM Elhagali… - ACS …, 2022 - ACS Publications
A series of thiazol-4-one/thiophene-bearing pyrazole derivatives as pharmacologically
attractive cores were initially synthesized using a hybridization approach. All structures were …
attractive cores were initially synthesized using a hybridization approach. All structures were …
Crystal engineering with pyrazolyl-thiazole derivatives: Structure-directing role of π-stacking and σ-hole interactions
The synthesis and X-ray characterization of 1-(2-(3-(4-bromophenyl)-5-(4-methoxyphenyl)-4,
5-dihydro-1H-pyrazol-1-yl)-4-methylthiazol-5-yl) ethanone (7), ethyl 2-(5-(4-bromophenyl)-3 …
5-dihydro-1H-pyrazol-1-yl)-4-methylthiazol-5-yl) ethanone (7), ethyl 2-(5-(4-bromophenyl)-3 …
Design, synthesis and antibacterial activity of N-aryl-3-(arylamino)-5-(((5-substituted furan-2-yl) methylene) amino)-1H-pyrazole-4-carboxamide as Nitrofurantoin® …
AS Hassan, GO Moustafa, NM Morsy… - Egyptian Journal of …, 2020 - ejchem.journals.ekb.eg
Nitrofurantoin® is an effective drug and used for treating urinary infectious diseases. A
series of nitrofurantoin® analogues bearing furan and pyrazole scaffolds as N-aryl-3 …
series of nitrofurantoin® analogues bearing furan and pyrazole scaffolds as N-aryl-3 …
Synthesis of new zirconium magnetic nanocomposite as a bioactive agent and green catalyst in the four-component synthesis of a novel multi-ring compound …
New nanocomposites containing zirconium were synthesized using microwave irradiation.
Their structure was confirmed by vibrating sample magnetometer (VSM) curves, X-ray …
Their structure was confirmed by vibrating sample magnetometer (VSM) curves, X-ray …
Design, Synthesis, Molecular Modeling and Biological Evaluation of Novel Pyrazole Benzimidazolone Derivatives as Potent Antioxidants
M Adardour, M Ait Lahcen, M Oubahmane, W Ettahiri… - Pharmaceuticals, 2023 - mdpi.com
In the present study, we used benzimidazolone as a starting material to efficiently synthesize
several hybrid compounds of pyrazole benzimidazolone derivatives by the 1, 3-dipolar …
several hybrid compounds of pyrazole benzimidazolone derivatives by the 1, 3-dipolar …
Synthesis of benzimidazole derivatives containing amide bond and biological evaluation as acetylcholinesterase, carbonic anhydrase I and II inhibitors
Acetylcholinesterase (AChE) and carbonic anhydrase I (CA-I) and II (CA-II) are two vital
metabolic enzymes. AChE inhibitors are seen as target molecules in drug development …
metabolic enzymes. AChE inhibitors are seen as target molecules in drug development …