MLIP and Its Potential Influence on Key Oncogenic Pathways
MN Hamwi, E Elsayed, H Dabash, A Abuawad… - Cells, 2024 - mdpi.com
Muscle-enriched A-type lamin-interacting protein (MLIP) is an emerging protein involved in
cellular homeostasis and stress adaptation. Eukaryotic cells regulate various cellular …
cellular homeostasis and stress adaptation. Eukaryotic cells regulate various cellular …
MLIP causes recessive myopathy with rhabdomyolysis, myalgia and baseline elevated serum creatine kinase
O Lopes Abath Neto, L Medne, S Donkervoort… - Brain, 2021 - academic.oup.com
Striated muscle needs to maintain cellular homeostasis in adaptation to increases in
physiological and metabolic demands. Failure to do so can result in rhabdomyolysis. The …
physiological and metabolic demands. Failure to do so can result in rhabdomyolysis. The …
MLIP genotype as a predictor of pharmacological response in primary open-angle glaucoma and ocular hypertension
MI Canut, O Villa, B Kudsieh, H Mattlin, I Banchs… - Scientific reports, 2021 - nature.com
Predicting the therapeutic response to ocular hypotensive drugs is crucial for the clinical
treatment and management of glaucoma. Our aim was to identify a possible genetic …
treatment and management of glaucoma. Our aim was to identify a possible genetic …
Muscle Enriched Lamin Interacting Protein (Mlip) Binds Chromatin and Is Required for Myoblast Differentiation
Muscle-enriched A-type lamin-interacting protein (Mlip) is a recently discovered Amniota
gene that encodes proteins of unknown biological function. Here we report Mlip's direct …
gene that encodes proteins of unknown biological function. Here we report Mlip's direct …
Biallelic truncating variants in the muscular A‐type lamin‐interacting protein (MLIP) gene cause myopathy with hyperCKemia
L Salzer‐Sheelo, A Fellner, N Orenstein… - European Journal of …, 2022 - Wiley Online Library
Background and purpose Muscular A‐type lamin‐interacting protein (MLIP) is most
abundantly expressed in cardiac and skeletal muscle. In vitro and animal studies have …
abundantly expressed in cardiac and skeletal muscle. In vitro and animal studies have …
MicroRNA205: A Key Regulator of Cardiomyocyte Transition from Proliferative to Hypertrophic Growth in the Neonatal Heart
The mammalian myocardium grows rapidly during early development due to cardiomyocyte
proliferation, which later transitions to cell hypertrophy to sustain the heart's postnatal …
proliferation, which later transitions to cell hypertrophy to sustain the heart's postnatal …
Novel homozygous nonsense mutation of MLIP and compensatory alternative splicing
J Mezreani, S Audet, F Martin, J Charbonneau… - NPJ Genomic …, 2022 - nature.com
Despite the growing accessibility of clinical sequencing, functional interpretation of variants
remains a major hurdle to molecular diagnostics of Mendelian diseases. We aimed to …
remains a major hurdle to molecular diagnostics of Mendelian diseases. We aimed to …
Nuclear isoform of FGF13 regulates post-natal neurogenesis in the hippocampus through an epigenomic mechanism
Q Yang, Y Zhai, H Wang, Y Cai, X Ma, Y Yin, Y Li… - Cell Reports, 2021 - cell.com
The hippocampus is one of two niches in the mammalian brain with persistent neurogenesis
into adulthood. The neurogenic capacity of hippocampal neural stem cells (NSCs) declines …
into adulthood. The neurogenic capacity of hippocampal neural stem cells (NSCs) declines …
A novel MLIP truncating variant in an 80-year-old patient with late-onset progressive weakness
L Bermejo-Guerrero, A Arteche-López… - Brain, 2022 - academic.oup.com
The MLIP gene (* 614106) encodes the muscular lamin A/C-interacting protein and has its
highest expression level in cardiac muscle, skeletal muscle and the brain. It has been linked …
highest expression level in cardiac muscle, skeletal muscle and the brain. It has been linked …
MLIP-Associated Myopathy: A Case Report and Review of the Literature
F Al Amrani, K Al-Thihli… - Journal of …, 2023 - content.iospress.com
Background: Muscular A-type lamin-interacting protein (MLIP) has a regulatory role in
myoblast differentiation and organization of myonuclear positioning in skeletal muscle. It is …
myoblast differentiation and organization of myonuclear positioning in skeletal muscle. It is …