Breast cancer chemotherapeutic options: A general overview on the preclinical validation of a multi-target Ruthenium (III) complex lodged in nucleolipid nanosystems

MG Ferraro, M Piccolo, G Misso, F Maione… - Cells, 2020 - mdpi.com
In this review we have showcased the preclinical development of original amphiphilic
nanomaterials designed for ruthenium-based anticancer treatments, to be placed within the …

Isolation and characterization of N‐(2‐Hydroxyethyl)hexadecanamide from Colletotrichum gloeosporioides with apoptosis‐inducing potential in breast cancer cells

N Rai, P Gupta, A Verma, SK Singh, V Gautam - BioFactors, 2023 - Wiley Online Library
Endophytic fungi are a well‐established reservoir of bioactive compounds that are
pharmaceutically valuable and therefore, contribute significantly to the biomedical field. The …

Melatonin is an appropriate candidate for breast cancer treatment: Based on known molecular mechanisms

N Amin, R Shafabakhsh, RJ Reiter… - Journal of cellular …, 2019 - Wiley Online Library
Breast cancer is the most prevalent cancer and one of the most important causes of death in
women throughout the world. Breast cancer risk factors include smoking, alcohol …

Melatonin has an inhibitory effect on MCF‐7 and MDA‐MB‐231 human breast cancer cell lines by inducing autophagy and apoptosis

GÖ Önder, G Sezer, S Özdamar… - Fundamental & Clinical …, 2022 - Wiley Online Library
The goal of this work was to see how melatonin affected Bax and Bcl‐2 expression, as well
as apoptosis and autophagy, in MCF‐7 and MDA‐MB‐231 breast cancer cell lines, which …

Apoptotic effects of valproic acid on miR-34a, miR-520h and HDAC1 gene in breast cancer

N Injinari, Z Amini-Farsani, M Yadollahi-Farsani… - Life Sciences, 2021 - Elsevier
Identifying miRNAs involved in cancer and devising strategies to control their expression is a
new therapeutic approach. Valproic acid (VPA) has attracted a lot of interest in cancer …

Pyrazole derivatives affinity to Estrogen receptor Alpha for breast cancer treatment evaluation using molecular docking

J Monga, NS Ghosh, S Kamboj… - Journal of Molecular …, 2023 - pubs.thesciencein.org
After lung cancer, which is the most common cancer overall, breast cancer is the second
most common cancer in women. Breast cancer is primarily brought on by 17-estradiol, a key …

miRNAs modulate the dichotomy of cisplatin resistance or sensitivity in breast cancer: an update of therapeutic implications

A Safi, M Bastami, S Delghir, K Ilkhani… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
Cisplatin has a broad-spectrum antitumor activity and is widely used for the treatment of
various malignant tumors. However, acquired or intrinsic resistance of cisplatin is a major …

New benzimidazoles targeting breast cancer: Synthesis, Pin1 inhibition, 2D NMR binding, and computational studies

S Nashaat, MA Henen, SM El-Messery, H Eisa - Molecules, 2022 - mdpi.com
Benzimidazole derivatives are known to be key players in the development of novel
anticancer agents. Herein, we aimed to synthesize novel derivatives to target breast cancer …

Effects of 1Hz 100mT electromagnetic field on apoptosis induction and Bax/Bcl-2 expression ratio in breast cancer cells

M Moori, D Norouzian, P Yaghmaei… - Multidisciplinary …, 2022 - mcijournal.com
Methods: In this study, induction of apoptosis was considered as one of the possible
mechanisms of ELF-EMFs on cancer inhibition. Breast cancer cell lines were exposed to a 1 …

Triple-Negative Breast Cancer, Cisplatin and Calpain-1

S Al-Bahlani, S Al-Jaaidi - Breast Cancer and Surgery, 2018 - books.google.com
Chemo-resistance of breast cancer is a major obstacle for successful treatment and is
mainly represented as a defect in apoptosis. The differential effects of platinum-based drugs …