Cost effectiveness of pharmacogenetic testing for drugs with clinical pharmacogenetics implementation consortium (CPIC) guidelines: a systematic review

SA Morris, AT Alsaidi, A Verbyla, A Cruz… - Clinical …, 2022 - Wiley Online Library
The objective of this study was to evaluate the evidence on cost‐effectiveness of
pharmacogenetic (PGx)–guided treatment for drugs with Clinical Pharmacogenetics …

Translating pharmacogenomics into clinical decisions: do not let the perfect be the enemy of the good

K Krebs, L Milani - Human genomics, 2019 - Springer
The field of pharmacogenomics (PGx) is gradually shifting from the reactive testing of single
genes toward the proactive testing of multiple genes to improve treatment outcomes, reduce …

Cost-effectiveness of pharmacogenetic-guided treatment: are we there yet?

M Verbelen, ME Weale, CM Lewis - The pharmacogenomics journal, 2017 - nature.com
Pharmacogenetics (PGx) has the potential to personalize pharmaceutical treatments. Many
relevant gene–drug associations have been discovered, but PGx-guided treatment needs to …

Economic evaluation in psychiatric pharmacogenomics: a systematic review

K Karamperis, M Koromina, P Papantoniou… - The …, 2021 - nature.com
Nowadays, many relevant drug–gene associations have been discovered, but
pharmacogenomics (PGx)-guided treatment needs to be cost-effective as well as clinically …

Genotype-guided warfarin therapy: current status

LC Tavares, LR Marcatto, PCJL Santos - Pharmacogenomics, 2018 - Taylor & Francis
Warfarin pharmacogenomics has been an extensively studied field in the last decades as it
is focused on personalized therapy to overcome the wide interpatient warfarin response …

Success stories in genomic medicine from resource-limited countries

K Mitropoulos, H Al Jaibeji, DA Forero, P Laissue… - Human genomics, 2015 - Springer
In recent years, the translation of genomic discoveries into mainstream medical practice and
public health has gained momentum, facilitated by the advent of new technologies …

Economic evaluation of pharmacogenomics: a value-based approach to pragmatic decision making in the face of complexity

SR Snyder, C Mitropoulou, GP Patrinos… - Public Health …, 2014 - karger.com
Evidence of the value of pharmacogenomic testing is needed to inform policymakers and
clinicians for decision making related to adoption and coverage, and to facilitate …

Genomic medicine without borders: which strategies should developing countries employ to invest in precision medicine? A new “fast-second winner” strategy

N CooperDavid, KV ReichardtJürgen… - OMICS: A Journal of …, 2017 - liebertpub.com
Genomic medicine has greatly matured in terms of its technical capabilities, but the diffusion
of genomic innovations worldwide faces significant barriers beyond mere access to …

Pharmacogenetic testing for adverse drug reaction prevention: systematic review of economic evaluations and the appraisal of quality matters for clinical practice and …

S Turongkaravee, J Jittikoon… - BMC Health Services …, 2021 - Springer
Background Genetic testing has potential roles in identifying whether an individual would
have risk of adverse drug reactions (ADRs) from a particular medicine. Robust cost …

Cost-effectiveness analysis of pharmacogenomics-guided clopidogrel treatment in Spanish patients undergoing percutaneous coronary intervention

V Fragoulakis, M Bartsakoulia… - The …, 2019 - nature.com
Clopidogrel is an antiplatelet drug given to patients before and after having a percutaneous
coronary intervention (PCI). Genomic variants in the CYP2C19 gene are associated with …