The interaction of drugs with biological membranes is a critical factor affecting their
pharmacokinetics and pharmacodynamics, so understanding how drugs interact with …

Mitochondria are arbiters in the fragile balance between cell life and death. These
organelles present an intricate membrane system, with a peculiar lipid composition and …

Abstract NRF2 (NFE2L2) is one of the main regulators of the antioxidant response of the cell.
Here we show that in cancer cells NRF2 targets are selectively upregulated or repressed …

ABSTRACT Z inc c luster transcription f actors (Zcfs) encoding zcf genes are exclusive for
fungi and required for multiple cellular processes including metabolism and development …

The postembryonic growth of skeletal muscle in teleost fish involves myoblast proliferation,
migration and differentiation, encompassing the main events of embryonic myogenesis …

Previous studies demonstrated that cells inhibit protein synthesis as a compensatory
mechanism for mitochondrial dysfunction. Protein synthesis can be attenuated by 1) the …

Neurodegenerative diseases have huge economic and societal impacts, and place an
immense emotional burden on patients and caregivers. Given that platelets have an …

Menadione, also known as vitamin K 3, is a 2-methyl-1, 4 naphthoquinone with a potent
cytotoxic activity mainly resulting from its quinone redox-cycling with production of reactive …

Diclofenac (DCF), the most widely consumed non-steroidal anti-inflammatory drug (NSAID)
worldwide, is associated with adverse typical effects, including gastrointestinal (GI) …

Lipidomics and proteomics have undergone a tremendous revolution, and the knowledge
about drugs' mechanism of action in biological membranes has been deepened. Methods to …