The complex metabolism of trimethylamine in humans: endogenous and exogenous sources

J Chhibber-Goel, A Gaur, V Singhal… - Expert Reviews in …, 2016 - cambridge.org
Trimethylamine (TMA) is a tertiary amine with a characteristic fishy odour. It is synthesised
from dietary constituents, including choline, L-carnitine, betaine and lecithin by the action of …

Investigating the root cause of N-nitrosodimethylamine formation in metformin pharmaceutical products

NEH Nasr, MG Metwaly, EO Ahmed… - Expert opinion on …, 2021 - Taylor & Francis
Background FDA limited N-nitrosodimethylamine (NDMA)–a carcinogenic impurity formed
during metformin (MET) tablets manufacturing–level to 96 ng/day; a step which led to recall …

Effects of dietary supplementation of primaLac, inulin, and biomin imbo on growth performance, antioxidant, and innate immune responses of common carp (Cyprinus …

A Ajdari, H Ghafarifarsani, SH Hoseinifar… - Aquaculture …, 2022 - Wiley Online Library
Prebiotics, probiotics, and synbiotics have been successfully used in dietary supplements to
achieve aquatic animal health and therefore increase the quality and sustainability of fish …

[HTML][HTML] In vivo induction of hepatocellular carcinoma by diethylnitrosoamine and pharmacological intervention in Balb C mice using Bergenia ciliata extracts

KK Dar, S Ali, M Ejaz, S Nasreen, N Ashraf… - Brazilian Journal of …, 2019 - SciELO Brasil
Background Hepatocellular carcinoma is the most frequent primary malignancy of liver and
accounts for as many as one million deaths worldwide in a year. Objectives The aim of the …

N‐nitrosamines induced infertility and hepatotoxicity in male rabbits

SA Sheweita, YY El Banna, M Balbaa… - Environmental …, 2017 - Wiley Online Library
N‐nitrosamines are widely spread environmental pollutants of well‐known toxicity and
carcinogenicity in various animal species. These compounds are metabolically activated by …

Sono-photodynamic modality for cancer treatment using bio-degradable bio-conjugated sonnelux nanocomposite in tumor-bearing mice: Activated cancer therapy …

SA Abd El-Kaream, GH Abd Elsamie… - Biochemical and …, 2018 - Elsevier
The underlying work was conducted aiming at cancer targeted therapy using the sono-
photodynamic therapy (SPDT) in combination with sonnelux (SLux) as a sono …

[PDF][PDF] Therapeutic and chemopreventive effects of nano curcumin against diethylnitrosamine induced hepatocellular carcinoma in rats

SK Hassan, AM Mousa, MG Eshak, A Farrag… - Int. J. Pharm. Pharm …, 2014 - researchgate.net
Objective: The present study is designed to investigate the preventive and therapeutic
effects of nano curcumin (Nano Cur) against diethylnitrosamine (DEN) induced …

Anti-Tumor Action, Clinical Biochemistry Profile and Phytochemical Constituents of a Pharmacologically Active Fraction of S. crispus in NMU-Induced Rat Mammary …

NS Yaacob, HM Yankuzo, S Devaraj, JKM Wong… - PLoS …, 2015 - journals.plos.org
Cancer patients seek alternative remedies such as traditional medicinal plants for safe and
effective treatment and help overcome the side effects of conventional therapy. Current …

[HTML][HTML] Biochemical and biophysical study of chemopreventive and chemotherapeutic anti-tumor potential of some Egyptian plant extracts

SA Abd El-Kaream - Biochemistry and biophysics reports, 2019 - Elsevier
Abstract the present study the was done to evaluate chemopreventive and
chemotherapeutic anti-tumor potential of some Egyptian plant extract (moringa, graviola …

Effects of Dietary Medlar (Mespilus germanica L.) Extract on Growth Performance, Innate Immune Characteristics, Antioxidant Status, and Responses to Crowding Stress in …

I Patra, AP Dewi, M Fawzi, F Hussam… - Aquaculture …, 2023 - Wiley Online Library
High stocking density is a stress factor that potentially affects physiological and immune
responses. In this study, the effects of medlar (Mespilus germanica) extract (ME) …