[HTML][HTML] Antioxidant phytochemicals for the prevention and treatment of chronic diseases
Overproduction of oxidants (reactive oxygen species and reactive nitrogen species) in the
human body is responsible for the pathogenesis of some diseases. The scavenging of these …
human body is responsible for the pathogenesis of some diseases. The scavenging of these …
[HTML][HTML] Saffron; An updated review on biological properties with special focus on cardiovascular effects
S Ghaffari, N Roshanravan - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Objective Saffron as a natural product has long been used to impede and treat different
disorders including cardiovascular disease (CVDs). Stigma is the most principal part of …
disorders including cardiovascular disease (CVDs). Stigma is the most principal part of …
Free radicals and the role of plant phytochemicals as antioxidants against oxidative stress-related diseases
GA Engwa - Phytochemicals: source of antioxidants and role in …, 2018 - books.google.com
Free radicals or reactive oxygen species (ROS) generated from various sources in the
environment as well as from cellular processes in the body are of serious health challenges …
environment as well as from cellular processes in the body are of serious health challenges …
[HTML][HTML] Crocin potentiates antioxidant defense system and improves oxidative damage in liver tissue in diabetic rats
Background Diabetes-induced oxidative stress has an essential role in hepatic dysfunction.
The current study was aimed to potentiate the impact of crocin treatment on the anti-oxidant …
The current study was aimed to potentiate the impact of crocin treatment on the anti-oxidant …
[HTML][HTML] Saffron: a natural potent antioxidant as a promising anti-obesity drug
Obesity is associated with various diseases, particularly diabetes, hypertension,
osteoarthritis and heart disease. Research on possibilities of herbal extracts and isolated …
osteoarthritis and heart disease. Research on possibilities of herbal extracts and isolated …
Active constituents of saffron (Crocus sativus L.) and their prospects in treating neurodegenerative diseases
W Yang, X Qiu, Q Wu, F Chang… - Experimental and …, 2023 - spandidos-publications.com
Crocus sativus L.(saffron) is widely used as a traditional spice for flavoring, coloring and
medicinal purposes. As a traditional Chinese herb, saffron promotes blood circulation …
medicinal purposes. As a traditional Chinese herb, saffron promotes blood circulation …
Crocin protects against doxorubicin-induced myocardial toxicity in rats through down-regulation of inflammatory and apoptic pathways
NM Elsherbiny, MF Salama, E Said… - Chemico-biological …, 2016 - Elsevier
Aim The clinical application of the chemotherapeutic agent; Doxorubicin (DOX) is limited by
its toxic effects on several body organs. The current study was conducted to evaluate the …
its toxic effects on several body organs. The current study was conducted to evaluate the …
Antioxidant, anti-inflammatory, and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats
Doxorubicin (DOX) is a well-known chemotherapeutic drug for most malignancies including
breast cancer and leukemia whilst the usage of DOX is limited owing to its cardiotoxicity. In …
breast cancer and leukemia whilst the usage of DOX is limited owing to its cardiotoxicity. In …
Sensitive analysis and simultaneous assessment of pharmacokinetic properties of crocin and crocetin after oral administration in rats
Y Zhang, F Fei, L Zhen, X Zhu, J Wang, S Li… - … of Chromatography B, 2017 - Elsevier
Crocin and crocetin in rat plasma were simultaneously analysed using ultra-performance
liquid chromatography tandem mass spectroscopy (UPLC–MS/MS), and method was fully …
liquid chromatography tandem mass spectroscopy (UPLC–MS/MS), and method was fully …
[HTML][HTML] Crocin protects against dexamethasone‑induced osteoblast apoptosis by inhibiting the ROS/Ca2+‑mediated mitochondrial pathway
Z Nie, S Deng, L Zhang, S Chen… - Molecular medicine …, 2019 - spandidos-publications.com
Osteoblast apoptosis has been identified as an important event in the development of
glucocorticoid (GC)‑induced osteoporosis and osteonecrosis of the femoral head. Crocin, a …
glucocorticoid (GC)‑induced osteoporosis and osteonecrosis of the femoral head. Crocin, a …