Analysis of anticancer drugs: a review
S Nussbaumer, P Bonnabry, JL Veuthey… - Talanta, 2011 - Elsevier
In the last decades, the number of patients receiving chemotherapy has considerably
increased. Given the toxicity of cytotoxic agents to humans (not only for patients but also for …
increased. Given the toxicity of cytotoxic agents to humans (not only for patients but also for …
[HTML][HTML] Optimization of 5-flurouracil solid-lipid nanoparticles: a preliminary study to treat colon cancer
AEB Yassin, MK Anwer, HA Mowafy… - … journal of medical …, 2010 - ncbi.nlm.nih.gov
Solid lipid nanoparticle (SLNs) formulae were utilized for the release of 5-flurouracil (5-FU)
inside the colonic medium for local treatment of colon cancer. SLNs were prepared by …
inside the colonic medium for local treatment of colon cancer. SLNs were prepared by …
[HTML][HTML] The use of chitosan-coated flexible liposomes as a remarkable carrier to enhance the antitumor efficacy of 5-fluorouracil against colorectal cancer
A Alomrani, M Badran, GI Harisa, M ALshehry… - Saudi pharmaceutical …, 2019 - Elsevier
Surface-coated nanocarriers have been extensively used to enhance the delivery of
anticancer drugs and improve their therapeutic index. In this study, chitosan (CS)-coated …
anticancer drugs and improve their therapeutic index. In this study, chitosan (CS)-coated …
Electrochemical behavior of an anticancer drug 5-fluorouracil at methylene blue modified carbon paste electrode
SD Bukkitgar, NP Shetti - Materials Science and Engineering: C, 2016 - Elsevier
A novel sensor for the determination of 5-fluorouracil was constructed by electrochemical
deposition of methylene blue on surface of carbon paste electrode. The electrode surface …
deposition of methylene blue on surface of carbon paste electrode. The electrode surface …
Preparation and characterization of polymeric nanoparticles surface modified with chitosan for target treatment of colorectal cancer
MM Badran, MM Mady, MM Ghannam… - International journal of …, 2017 - Elsevier
Fluorouracil (5-FU) loaded chitosan (C) coated polylactic-co-glycolic acid (PLGA)
nanoparticles [NPs](C-5-FU PLGA NPs) and polycaprolactone [PCL](C-5-FU PCL NPs) were …
nanoparticles [NPs](C-5-FU PLGA NPs) and polycaprolactone [PCL](C-5-FU PCL NPs) were …
The design of anionic surfactant-based amino-functionalized mesoporous silica nanoparticles and their application in transdermal drug delivery
A Almomen, AM El-Toni, M Badran, A Alhowyan… - Pharmaceutics, 2020 - mdpi.com
Melanoma remains the most lethal form of skin cancer and most challenging to treat despite
advances in the oncology field. Our work describes the utilization of nanotechnology to …
advances in the oncology field. Our work describes the utilization of nanotechnology to …
Mesoporous silica nanoparticles coated with carboxymethyl chitosan for 5-fluorouracil ocular delivery: characterization, in vitro and in vivo studies
This study investigates the development of topically applied non-invasive amino-
functionalized silica nanoparticles (AMSN) and O-Carboxymethyl chitosan-coated AMSN …
functionalized silica nanoparticles (AMSN) and O-Carboxymethyl chitosan-coated AMSN …
[HTML][HTML] Prolonged exposure of colon cancer cells to 5-fluorouracil nanoparticles improves its anticancer activity
In this study, we aimed to improve the anticancer effect of 5-FU on human colon cancer cell
lines by incorporating in poly (d, l lactic-co-glycolic acid)(PLGA) nanoparticles (NPs). The 5 …
lines by incorporating in poly (d, l lactic-co-glycolic acid)(PLGA) nanoparticles (NPs). The 5 …
Electrochemical behavior of anticancer drug 5-fluorouracil at carbon paste electrode and its analytical application
SD Bukkitgar, NP Shetti - Journal of Analytical Science and Technology, 2016 - Springer
Background A set of pyrimidine nucleobase present in all living systems as a component of
nucleic acid constitutes uracil together with thymine and cytosine. A diverse physiological …
nucleic acid constitutes uracil together with thymine and cytosine. A diverse physiological …
Eudragit-Coated Sporopollenin Exine Microcapsules (SEMC) of Phoenix dactylifera L. of 5-Fluorouracil for Colon-Specific Drug Delivery
In this study, 5-fluorouracil (5-FU)-loaded pollens of Phoenix dactylifera and their coating
with ERS was done and evaluated for the colon-targeted delivery of 5-FU to treat colon …
with ERS was done and evaluated for the colon-targeted delivery of 5-FU to treat colon …