Natural products, and especially the active ingredients found in traditional Chinese medicine
(TCM), have a thousand-year-long history of clinical use and a strong theoretical basis in …

Andrographis paniculata (A. paniculata) is a medicinal plant traditionally used as anti-
inflammation and anti-bacteria herb. Andrographolide, the major active component of A …

The precise mechanism through which macroautophagy/autophagy affects psoriasis is
poorly understood. Here, we found that keratinocyte (KC) autophagy, which was positively …

The diterpene lactone andrographolide, isolated from Andrographis paniculata, has been
proven to possess several important protective biological activities, including antioxidant …

Andrographis paniculata has long been part of the traditional herbal medicine system in
Asia and in Scandinavia. Andrographolide was isolated as a major bioactive constituent of …

Botanicals have attracted much attention in the field of anti-inflammatory due to their good
pharmacological activity and efficacy. Andrographis paniculata is a natural plant ingredient …

Psoriasis is a complex chronic inflammatory skin disease with unclear molecular
mechanisms. We found that the Src homology‐2 domain‐containing protein tyrosine …

Bony fusion caused by pathological new bone formation manifests the clinical feature of
ankylosing spondylitis (AS). However, the underlying mechanism remains elusive. Here we …

Psoriasis is an incurable, chronic inflammatory disease, which brings a substantial burden
on individuals and society. Currently, the treatment of psoriasis has entered the era of …

Background Psoriasis is an immune-mediated chronic inflammatory skin disease
characterized by well-defined erythema and white scales, which affects approximately 2% of …