The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …

Recent years have seen several advances in our understanding of immunity to virus
infection of the lower respiratory tract, including to influenza virus infection. Here, we review …

Adaptation of the endoplasmic reticulum (ER) pathway for MHC class I (MHC-I) presentation
in dendritic cells enables cross-presentation of peptides derived from phagocytosed …

A cardinal feature of COVID-19 is lung inflammation and respiratory failure. In a prospective
multi-country cohort of COVID-19 patients, we found that increased Notch4 expression on …

В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

The lung is highly exposed to the external environment. For this reason, the lung needs to
handle a number of potential threats present in inhaled air such as viruses or bacteria …

Influenza virus infection is a serious threat to humans and animals, with the potential to
cause severe pneumonia and death. Annual vaccination strategies are a mainstay to …

Adaptations in maternal systemic immunity are presumed to be responsible for observed
alterations in disease susceptibility and severity as pregnancy progresses. Epidemiological …

Immune responses to lung infections must be tightly regulated in order to permit pathogen
eradication while maintaining organ function. Exuberant or dysregulated inflammation can …

Lymph nodes, particularly thoracic lymph nodes, are among the most common sites of
extrapulmonary tuberculosis (TB). However, Mycobacterium tuberculosis (Mtb) infection in …