The fungal cell wall is essential for growth and survival, and is a key target for antifungal
drugs and the immune system. The cell wall must be robust but flexible, protective and …

Talaromycosis (Penicilliosis) is an opportunistic mycosis caused by the thermally dimorphic
fungus Talaromyces (Penicillium) marneffei. Similar to other major causes of systemic …

The adverse outcomes of fungal infection in mammalian hosts depend on the complex
interactions between the host immune system and pathogen virulence-associated traits. The …

Glycoside hydrolases (GHs) are enzymes that participate in many biological processes of
fungi and other organisms by hydrolyzing glycosidic linkages in glycosides. They play …

One of the most challenging aspects of long-term research based on microorganisms is the
maintenance of isolates under ex situ conditions, particularly the conservation of …

In recent years, the increased frequency of drug-resistant strains of Cryptococcus
neoformans has depleted our antifungal armory. In the present study, we investigated the …

Coenzyme Q (CoQ) or ubiquinone functions as an electron transporter in the electron
transport system in both prokaryotes and eukaryotes. The isoprenyl side chain of CoQ is …

Two new rearranged 2, 3-seco-tirucallane triterpenoids, meliadubins A (1) and B (2), along
with four known compounds, 3–6, were isolated from the barks of Melia dubia Cav …

Sporothrix brasiliensis is an emerging fungal pathogen frequently associated with zoonotic
transmission of sporotrichosis by contaminated cats. Within 25 years, the disease has …

Melanin is an Aspergillus flavus cell wall component that provides chemical and physical
protection to the organism. However, the molecular and biological mechanisms modulating …