Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

Migraine is an extremely disabling, common neurological disorder characterized by a
complex neurobiology, involving a series of central and peripheral nervous system areas …

Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

Light exerts a range of powerful biological effects beyond image vision, including mood and
learning regulation. While the source of photic information affecting mood and cognitive …

Understanding the mechanisms of migraine remains challenging as migraine is not a static
disorder, and even in its episodic form migraine remains an “evolutive” chronic condition …

Cluster headache is a trigeminal autonomic cephalalgia characterised by extremely painful,
strictly unilateral, short-lasting headache attacks accompanied by ipsilateral autonomic …

Scientific evidence supports the notion that migraine pathophysiology involves inherited
alteration of brain excitability, intracranial arterial dilatation, recurrent activation, and …

The melanopsin-expressing, intrinsically photosensitive retinal ganglion cells (ipRGCs) are
a relatively recently discovered class of atypical ganglion cell photoreceptor. These ipRGCs …

Migraine is a collection of perplexing neurological conditions in which the brain and its
associated tissues have been implicated as major players during an attack. Once …

Migraine is a neurological disorder that manifests as a debilitating headache associated
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …