Applications of the Morris water maze in translational traumatic brain injury research

LB Tucker, AG Velosky, JT McCabe - Neuroscience & Biobehavioral …, 2018 - Elsevier
Acquired traumatic brain injury (TBI) is frequently accompanied by persistent cognitive
symptoms, including executive function disruptions and memory deficits. The Morris Water …

The rat animal model for noise-induced hearing loss

CD Escabi, MD Frye, M Trevino… - The Journal of the …, 2019 - pubs.aip.org
Rats make excellent models for the study of medical, biological, genetic, and behavioral
phenomena given their adaptability, robustness, survivability, and intelligence. The rat's …

Behavioral deficits in animal models of blast traumatic brain injury

A Aravind, AR Ravula, N Chandra, BJ Pfister - Frontiers in neurology, 2020 - frontiersin.org
Blast exposure has been identified to be the most common cause for traumatic brain injury
(TBI) in soldiers. Over the years, rodent models to mimic blast exposures and the behavioral …

Remodeling of cholinergic input to the hippocampus after noise exposure and tinnitus induction in Guinea pigs

L Zhang, C Wu, DT Martel, M West, MA Sutton… - …, 2019 - Wiley Online Library
Here, we investigate remodeling of hippocampal cholinergic inputs after noise exposure and
determine the relevance of these changes to tinnitus. To assess the effects of noise …

Review of blast noise and the auditory system

CB Paik, M Pei, JS Oghalai - Hearing research, 2022 - Elsevier
The auditory system is particularly vulnerable to blast injury due to the ear's role as a highly
sensitive pressure transducer. Over the past several decades, studies have used a variety of …

Single-prolonged stress impairs prefrontal cortex control of amygdala and striatum in rats

VM Piggott, KE Bosse, MJ Lisieski… - Frontiers in Behavioral …, 2019 - frontiersin.org
Medial prefrontal cortex (mPFC), amygdala, and striatum neurocircuitry has been shown to
play an important role in post-traumatic stress disorder (PTSD) pathology in humans …

Blast-induced central auditory neurodegeneration affects tinnitus development regardless of peripheral cochlear damage

T Kurioka, K Mizutari, Y Satoh, Y Kobayashi… - Journal of …, 2024 - liebertpub.com
Blast exposure causes serious complications, the most common of which are ear-related
symptoms such as hearing loss and tinnitus. The blast shock waves can cause …

Central and peripheral auditory abnormalities in chinchilla animal model of blast-injury

N Shao, S Jiang, D Younger, T Chen, M Brown… - Hearing research, 2021 - Elsevier
Exposure to blast overpressure or high-intensity sound can cause injuries to the auditory
system, which leads to hearing loss or tinnitus. In this study, we examined the involvement of …

Auditory Brainstem Responses (ABR) of rats during experimentally induced tinnitus: literature review

E Domarecka, H Olze, AJ Szczepek - Brain Sciences, 2020 - mdpi.com
Tinnitus is a subjective phantom sound perceived only by the affected person and a
symptom of various auditory and non-auditory conditions. The majority of methods used in …

[HTML][HTML] The rat as a model for studying noise injury and otoprotection

AG Holt, A Kühl, RD Braun, R Altschuler - The Journal of the Acoustical …, 2019 - pubs.aip.org
A major challenge for those studying noise-induced injury pre-clinically is the selection of an
animal model. Noise injury models are particularly relevant in an age when people are …