Age-related macular degeneration (AMD) is a complex eye disorder and is the leading
cause of incurable blindness worldwide in the elderly. Clinically, AMD initially affects the …

Background Visual impairment in elderly people is a considerable health problem that
significantly affects quality of life of millions worldwide. The magnitude of this issue is …

A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …

The complement system is an essential element of the innate immune response that
becomes activated upon recognition of molecular patterns associated with microorganisms …

Age-related macular degeneration (AMD) is a major cause of blindness in the elderly. We
report a genome-wide screen of 96 cases and 50 controls for polymorphisms associated …

Age-related macular degeneration is the leading cause of irreversible blindness in people
50 years of age or older in the developed world. This article reviews the clinical and …

Age-related macular degeneration (AMD) is a leading cause of visual impairment and
blindness in the elderly whose etiology remains largely unknown. Previous studies identified …

Age-related macular degeneration (AMD) is a common, late-onset, and complex trait with
multiple risk factors. Concentrating on a region harboring a locus for AMD on 1q25-31, the …

The factor H (FH) protein family is emerging as a complex network of proteins controlling the
fate of the complement alternative pathway (AP) and dictating susceptibility to a wide range …

The complement system is an essential component of the innate immune system that
participates in elimination of pathogens and altered host cells and comprises an essential …