Blood-brain barrier dysfunction and recovery after ischemic stroke
The blood-brain barrier (BBB) plays a vital role in regulating the trafficking of fluid, solutes
and cells at the blood-brain interface and maintaining the homeostatic microenvironment of …
and cells at the blood-brain interface and maintaining the homeostatic microenvironment of …
Human astrocytes: structure and functions in the healthy brain
Data collected on astrocytes' physiology in the rodent have placed them as key regulators of
synaptic, neuronal, network, and cognitive functions. While these findings proved highly …
synaptic, neuronal, network, and cognitive functions. While these findings proved highly …
[HTML][HTML] Astrocytic activation generates de novo neuronal potentiation and memory enhancement
Astrocytes respond to neuronal activity and were shown to be necessary for plasticity and
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …
Astrocyte activation in neurovascular damage and repair following ischaemic stroke
A Patabendige, A Singh, S Jenkins, J Sen… - International journal of …, 2021 - mdpi.com
Transient or permanent loss of tissue perfusion due to ischaemic stroke can lead to damage
to the neurovasculature, and disrupt brain homeostasis, causing long-term motor and …
to the neurovasculature, and disrupt brain homeostasis, causing long-term motor and …
From synapses to circuits, astrocytes regulate behavior
Astrocytes are non-neuronal cells that regulate synapses, neuronal circuits, and behavior.
Astrocytes ensheath neuronal synapses to form the tripartite synapse where astrocytes …
Astrocytes ensheath neuronal synapses to form the tripartite synapse where astrocytes …
[HTML][HTML] Human astrocytes in the diseased brain
Astrocytes are key active elements of the brain that contribute to information processing.
They not only provide neurons with metabolic and structural support, but also regulate …
They not only provide neurons with metabolic and structural support, but also regulate …
Astrocytes as a therapeutic target in alzheimer's disease–comprehensive review and recent developments
M Rodríguez-Giraldo, RE González-Reyes… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is a frequent and disabling neurodegenerative disorder, in which
astrocytes participate in several pathophysiological processes including neuroinflammation …
astrocytes participate in several pathophysiological processes including neuroinflammation …
Reactive glia inflammatory signaling pathways and epilepsy
P Sanz, MA Garcia-Gimeno - International journal of molecular sciences, 2020 - mdpi.com
Neuroinflammation and epilepsy are interconnected. Brain inflammation promotes neuronal
hyper-excitability and seizures, and dysregulation in the glia immune-inflammatory function …
hyper-excitability and seizures, and dysregulation in the glia immune-inflammatory function …
[HTML][HTML] Astrocytes: a double-edged sword in neurodegenerative diseases
ZB Ding, LJ Song, Q Wang, G Kumar… - Neural regeneration …, 2021 - journals.lww.com
Astrocytes play multifaceted and vital roles in maintaining neurophysiological function of the
central nervous system by regulating homeostasis, increasing synaptic plasticity, and …
central nervous system by regulating homeostasis, increasing synaptic plasticity, and …
[HTML][HTML] An overview on the differential interplay among neurons–astrocytes–microglia in CA1 and CA3 hippocampus in hypoxia/ischemia
D Lana, F Ugolini, MG Giovannini - Frontiers in cellular neuroscience, 2020 - frontiersin.org
Neurons have been long regarded as the basic functional cells of the brain, whereas
astrocytes and microglia only as elements of support. However, proper intercommunication …
astrocytes and microglia only as elements of support. However, proper intercommunication …