We review progress towards greater mechanistic understanding and clinical translation of a
strategy to improve respiratory and non-respiratory motor function in people with …

Surface electromyography (sEMG) can be used to measure the electrical activity of the
respiratory muscles. The possible applications of sEMG span from patients suffering from …

Severe hypoxia can induce a range of systemic disorders; however, surprising resilience
can be obtained through sublethal adaptation to hypoxia, a process termed as hypoxic …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative condition noteworthy for upper
and lower motor neuron death. Involvement of respiratory motor neuron pools leads to …

Widespread appreciation that neuroplasticity is an essential feature of the neural system
controlling breathing has emerged only in recent years. In this chapter, we focus on …

Plasticity is a fundamental property of the neural system controlling breathing. One key
example of respiratory motor plasticity is phrenic long-term facilitation (pLTF), a persistent …

Intermittent hypoxia-hyperoxia training (IHHT) is a non-pharmacological therapeutic
modality for management of some chronic-and age-related pathologies, such as Alzheimer's …

Moderate acute intermittent hypoxia (mAIH) elicits a form of phrenic motor plasticity known
as phrenic long-term facilitation (pLTF), which requires spinal 5-HT2 receptor activation …

Plasticity is a fundamental property of the neuromotor system controlling breathing. One key
example of respiratory motor plasticity is phrenic long-term facilitation (pLTF), a persistent …

Abstract Alzheimer's disease (AD), characterized by severe and progressive cognitive
decline, stands as one of the most prevalent and devastating forms of dementia. Based on …