Blood-derived biomarkers for brain and spinal cord diseases are urgently needed. The
introduction of highly sensitive immunoassays led to a rapid increase in the number of …

Background The use of blood biomarkers after mild traumatic brain injury (mTBI) has been
widely studied. We have identified eight unresolved issues related to the use of five …

Abstract HUIBREGTSE, ME, Bazarian, JJ, Shultz, SR, and Kawata K. The biological
significance and clinical utility of emerging blood biomarkers for traumatic brain injury …

Biomarkers such as calcium channel binding protein S100 subunit beta (S100B), glial
fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase L1 (UCH-L1) and neuron …

Objective: Identification and validation of blood-based biomarkers for the diagnosis and
prognosis of mild traumatic brain injury (mTBI) is of critical importance. There have been …

Older adults have the highest incidence of traumatic brain injury globally. Accurate blood-
based biomarkers are needed to assist with diagnosis of patients across the spectrum of age …

Despite the often seemingly innocuous nature of a mild traumatic brain injury (mTBI), its
consequences can be devastating, comprising debilitating symptoms that interfere with daily …

A lack of convenient and reliable biomarkers for diagnosis and prognosis is a common
challenge for neurodegenerative diseases such as Alzheimer's disease (AD). Recent …

Traumatic brain injury (TBI) is a complex and multifaceted disorder that has become a
significant public health concern worldwide due to its contribution to mortality and morbidity …

Considerable advancements have been made in the quantification of biofluid-based
biomarkers for traumatic brain injury (TBI), which provide a clinically accessible window to …