[HTML][HTML] Reactive gliosis in traumatic brain injury: a comprehensive review

Z Amlerova, M Chmelova, M Anderova… - Frontiers in Cellular …, 2024 - frontiersin.org
Traumatic brain injury (TBI) is one of the most common pathological conditions impacting the
central nervous system (CNS). A neurological deficit associated with TBI results from a …

Divergent spatial learning, enhanced neuronal transcription, and blood–brain barrier disruption develop during recovery from post-injury sleep fragmentation

ZM Tapp, C Ren, K Palmer, J Kumar, RR Atluri… - Neurotrauma …, 2023 - liebertpub.com
Traumatic brain injury (TBI) causes pathophysiology that may significantly decrease quality
of life over time. A major propagator of this response is chronic, maladaptive …

[HTML][HTML] Delayed TBI-induced neuronal death in the ipsilateral hippocampus and behavioral deficits in rats: influence of corticosterone-dependent survivorship bias?

I Komoltsev, D Shalneva, O Kostyunina… - International journal of …, 2023 - mdpi.com
Acute and chronic corticosterone (CS) elevations after traumatic brain injury (TBI) may be
involved in distant hippocampal damage and the development of late posttraumatic …

Multiparity differentially affects specific aspects of the acute neuroinflammatory response to traumatic brain injury in female mice

R Gilfarb, Z Tapp, E Lemanski, J Velasquez… - Neuroscience, 2023 - Elsevier
Pregnancy is associated with profound acute and long-term physiological changes, but the
effects of such changes on brain injury outcomes are unclear. Here, we examined the effects …

[HTML][HTML] Disturbances in fear extinction learning after mild traumatic brain injury in mice are accompanied by alterations in dendritic plasticity in the medial prefrontal …

JA Babb, A Zuberer, S Heinrichs, KK Rumbika… - Brain Research …, 2023 - Elsevier
Mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD) have emerged
as the signature injuries of the US veterans who served in Iraq and Afghanistan, and …

[HTML][HTML] Sleep fragmentation after traumatic brain injury impairs behavior and conveys long-lasting impacts on neuroinflammation

S Houle, Z Tapp, S Dobres, S Ahsan, Y Reyes… - Brain, Behavior, & …, 2024 - Elsevier
Traumatic brain injury (TBI) causes a prolonged inflammatory response in the central
nervous system (CNS) driven by microglia. Microglial reactivity is exacerbated by stress …

IDO‐1 inhibition improves outcome after fluid percussion injury in adult male rats

M Sadek, KR Stover, X Liu, MA Reed… - Journal of …, 2024 - Wiley Online Library
Abstract The enzyme indoleamine 2, 3 dioxygenase 1 (IDO1) catalyzes the rate‐limiting step
in the kynurenine pathway (KP) which produces both neuroprotective and neurotoxic …

Neuroimmune Responses to Sleep Disturbances after Traumatic Brain Injury

Z Tapp - 2023 - rave.ohiolink.edu
Traumatic brain injury (TBI) is the leading cause of injury-induced disabilities that decrease
quality of life. Neuroinflammation propagated by immune cells like microglia causes or …

Investigating the Effects of IDO1 Inhibition on the Recovery of Motor Coordination, Memory and Mood Following TBI

M Sadek - 2023 - search.proquest.com
Traumatic brain injury (TBI) is caused by mechanistic forces that impact the brain, leading to
neuronal damage and deterioration. Secondary injuries, such as neuroinflammation, can …

[PDF][PDF] Recovery from Chronic Sleep Fragmentation after Traumatic Brain Injury Does Not Cause Lasting Deficits in Cognitive Behavior

K Palmer - 2022 - kb.osu.edu
Traumatic brain injury (TBI) impairs cognitive function of learning and memory, which can be
worsened by post-TBI stressors. Many stressors cause sleep disturbances in the TBI …