Extracellular vesicles (EVs), lipid bilayer-enclosed structures that contain a variety of
biological molecules shed by cells, are increasingly becoming appreciated as a major form …

When released into biological fluids like blood or saliva, brain extracellular vesicles (EVs)
might provide a window into otherwise inaccessible tissue, contributing useful biomarkers of …

It is now acknowledged that extracellular vesicles (EVs) are important effectors in a vast
number of biological processes through intercellular transfer of biomolecules. Increasing …

Tumour metastasis is the main cause of cancer related deaths. Metastasis is an intricate
multi-step process that requires the acquisition of several cancer cell features, including the …

Glycans are major constituents of extracellular vesicles (EVs). Alterations in the
glycosylation pathway are a common feature of cancer cells, which gives rise to de novo or …

Mesenchymal stem cells (MSCs) exert therapeutic effect on treating acute myocardial
infarction. Recent evidence showed that paracrine function rather than direct differentiation …

O-glycosylation is a highly frequent post-translation modification of proteins, with important
functional implications in both physiological and disease contexts. The biosynthesis of O …

Glioblastoma multiforme (GBM) is a lethal disease characterized by an overall survival of
about 1 year, making it one of the most aggressive tumours, with very limited therapeutic …

Increasing attention has been given to secreted extracellular vesicles (EVs) in the past
decades, especially in the portrayal of their molecular cargo and role as messengers in both …

Studies involving the functional analysis of exosomal contents including proteins, DNA, and
RNA have been reported. Most membrane proteins and lipids are glycosylated, which …