Retinal microvasculature as a model to study the manifestations of hypertension

CY Cheung, MK Ikram, C Sabanayagam, TY Wong - Hypertension, 2012 - Am Heart Assoc
The retinal vasculature allows direct noninvasive visualization of the body's
mircrovasculature. Because the retina and other end organs (brain and kidney) share similar …

Blood vessel segmentation of fundus images by major vessel extraction and subimage classification

S Roychowdhury, DD Koozekanani… - IEEE journal of …, 2014 - ieeexplore.ieee.org
This paper presents a novel three-stage blood vessel segmentation algorithm using fundus
photographs. In the first stage, the green plane of a fundus image is preprocessed to extract …

Iterative vessel segmentation of fundus images

S Roychowdhury, DD Koozekanani… - IEEE Transactions on …, 2015 - ieeexplore.ieee.org
This paper presents a novel unsupervised iterative blood vessel segmentation algorithm
using fundus images. First, a vessel enhanced image is generated by tophat reconstruction …

Systemic associations of dynamic retinal vessel analysis: a review of current literature

M Lim, MB Sasongko, MK Ikram, E Lamoureux… - …, 2013 - Wiley Online Library
Endothelial dysfunction is a key pathogenic mechanism of CVD. The retinal microvascular
network offers a unique, non‐invasive window to study endothelial function. Recently …

[HTML][HTML] Non-invasive retinal blood vessel wall measurements with polarization-sensitive optical coherence tomography for diabetes assessment: A quantitative study

H Afsharan, D Silva, C Joo, B Cense - Biomolecules, 2023 - mdpi.com
Diabetes affects the structure of the blood vessel walls. Since the blood vessel walls are
made of birefringent organized tissue, any change or damage to this organization can be …

Altered retinal cerebral vessel oscillation frequencies in Alzheimer's disease compatible with impaired amyloid clearance

K Kotliar, M Ortner, A Conradi, P Hacker, C Hauser… - Neurobiology of …, 2022 - Elsevier
Retinal vessels are similar to cerebral vessels in their structure and function. Moderately low
oscillation frequencies of around 0.1 Hz have been reported as the driving force for …

[HTML][HTML] Age-related focal loss of contractile vascular smooth muscle cells in retinal arterioles is accelerated by caveolin-1 deficiency

AM Reagan, X Gu, S Paudel, NM Ashpole, M Zalles… - Neurobiology of …, 2018 - Elsevier
Cerebral microcirculation is critical for the preservation of brain health, and vascular
impairment is associated with age-related neurodegenerative diseases. Because the retina …

[HTML][HTML] Factors determining flicker-induced retinal vasodilation in healthy subjects

M Sharifizad, KJ Witkowska… - … & Visual Science, 2016 - iovs.arvojournals.org
Purpose: The purpose of this study was to analyze factors determining retinal arterial and
venous responses to stimulation with diffuse luminance flicker in healthy subjects. Methods …

Assessing vascular function using dynamic retinal diameter measurements: a new insight on the endothelium

R Heitmar, RJ Summers - Thrombosis and haemostasis, 2012 - thieme-connect.com
Reliable assessment of endothelial function is important for the diagnosis, risk prediction
and treatment-monitoring in cardiovascular disease. Numerous techniques exist such as …

[HTML][HTML] Hypertension-associated changes in retinal blood vessel walls measured in vivo with polarization-sensitive optical coherence tomography

H Afsharan, V Anilkumar, D Silva, G Dwivedi… - Optics and Lasers in …, 2024 - Elsevier
Blood vessel walls are made of organized fibrous tissue with intrinsic birefringence. Even in
its very early stages, hypertension can change the structure of a blood vessel wall. In this …