Mechanochemistry of collagen

SM Siadat, JW Ruberti - Acta Biomaterialia, 2023 - Elsevier
The collagen molecular family is the result of nearly one billion years of evolution. It is a
unique family of proteins, the majority of which provide general mechanical support to …

[HTML][HTML] Tension in the ranks: Cooperative cell contractions drive force-dependent collagen assembly in human fibroblast culture

AA Silverman, JD Olszewski, SM Siadat, JW Ruberti - Matter, 2024 - cell.com
Currently, there is no mechanistic model that fully explains the initial synthesis and
organization of durable animal structure. As a result, our understanding of extracellular …

Effect of polyacrylamide gel elasticity on collagen type II fibril assembly

KG Wilcox, S Kramer, S Chatterjee, A Linscott… - Soft Matter, 2024 - pubs.rsc.org
Collagen type II fibrils provide structural integrity to the articular cartilage extracellular matrix.
However, the conditions that control the fibril radial size scale, distribution, and formation …

Soluble allogeneic telocollagen as a direct protein therapeutic: results of serial injections in a rodent rotator cuff tear model

LS Oh, AA Silverman, N Rossi, MA Randolph… - Journal of Shoulder and …, 2024 - Elsevier
Hypothesis Delivery of soluble allogeneic type I telocollagen (allo-telocollagen) will
accelerate and improve the healing of damaged tendons. Our hypothesis draws from known …

The Role of Integrin Receptor's α and β Subunits of Mouse Mesenchymal Stem Cells on the Interaction of Marine-Derived Blacktip Reef Shark (Carcharhinus …

B Ge, M Wei, B Bao, Z Pan, J Elango, W Wu - International Journal of …, 2023 - mdpi.com
Marine collagen (MC) has recently attracted more attention in tissue engineering as a
biomaterial substitute due to its significant role in cellular signaling mechanisms, especially …

Elasticity of Biomacromolecular Helices and the Effect of Elasticity on Biological Assembly

KG Wilcox - 2024 - search.proquest.com
Helices are abundant and crucial examples of rigidity throughout biology from protein lever
arms in molecular motors to collagen type II that assembles into fibrils in the extracellular …

蛍光顕微鏡によるコラーゲン原線維の再構成過程の観察

田端優貴, 山本憲隆 - バイオフロンティア講演会講演論文集2022.33, 2022 - jstage.jst.go.jp
腱・靱帯は階層構造をとっており, 線維束, 線維, 原線維, サブフィブリル, マイクロフィブリルの順に
細かくなり, 最終的にはコラーゲン分子に至る. コラーゲン分子は直径約 1.5 nm, 長さ約 300nm …