▪ Abstract Apoptosis of mature T lymphocytes preserves peripheral homeostasis and
tolerance by countering the profound changes in the number and types of T cells stimulated …

▪ Abstract Apoptosis is a highly regulated process of cell death that is required for the
development and homeostasis of multicellular organisms. In contrast to necrosis, apoptosis …

Despite the importance of glucocorticoids (GCs) to modern medicine, the physiological role
of endogenous corticostcroids in immunomodulation is poorly understood. This article …

Over the last three decades considerable evidence has accumulated that CD8+ T cells
regulate peripheral immune responses, in part, by specifically controlling the outgrowth of …

Proteins encoded by the fas and fas ligand (fasL) genes are involved in apoptotic cell death
in lymphocytes. In this article we review the recent elucidation of the role of the Fas-Fast …

Interactions mediated by TCRs expressed on different T cell subsets may play a role in
immunoregulation. To investigate this idea, we studied the regulation of superantigen …

Administration of staphylococcal enterotoxin B (SEB) to BALB/c mice was found to induce a
cytokine release syndrome hallmarked by weight loss and hypoglycemia. A neutralizing …

The immune system plays an important role in the regulation of tissue homeostasis (" tissue
immune physiology"). Function of distinct tissues during adulthood, including the ovary …

Glucocorticoids are believed to play a role in T cell development and selection, although
their precise function is controversial. Glucocorticoid receptor (GR)-deficient mice were used …

Resting mature T lymphocytes are activated when triggered via their antigen-specific T-cell
receptor (TCR) to elicit an appropriate immune response. In contrast, preactivated T cells …