Stress is a central concept in biology and has now been widely used in psychological,
physiological, social, and even environmental fields. However, the concept of stress was …

Accumulating evidence shows that deregulation of fatty acid (FA) metabolism is associated
with the development of cancer. Long-chain acyl-coenzyme A synthases (ACSLs) are …

Oxidative stress and AKT serine-threonine kinase (AKT) are responsible for regulating
several cell functions of cancer cells. Several natural products modulate both oxidative …

Group 3 innate lymphoid cells (ILC3s) are key players in intestinal homeostasis. ER stress is
linked to inflammatory bowel disease (IBD). Here, we used cell culture, mouse models, and …

Neuronal death and inflammatory response are two common pathological hallmarks of
acute central nervous system injury and chronic degenerative disorders, both of which are …

Background Medical students have high levels of stress, which is associated with higher
incidents of burnout, depression, and suicide compared to age-matched peers. Mindfulness …

Damage-associated molecular patterns (DAMPs) are endogenous molecules that are
released from host cells as a result of cell death or damage. The release of DAMPs in …

Intelectin-1 (ITLN1) is a lectin secreted by intestinal epithelial cells (IECs) and upregulated in
human ulcerative colitis (UC). We investigated how ITLN1 production is regulated in IECs …

Abstract Background Shaoyao Decoction (SYD) is a canonical herbal medicine prescription
formulated by Liu Wan-Su in AD 1186. SYD has been widely used to treat inflammatory …

Genetic variants in the DNA methyltransferase 3 A (DNMT3A) locus have been associated
with inflammatory bowel disease (IBD). DNMT3A is part of the epigenetic machinery …