Visual processing in the fly, from photoreceptors to behavior

TA Currier, MM Pang, TR Clandinin - Genetics, 2023 - academic.oup.com
Originally a genetic model organism, the experimental use of Drosophila melanogaster has
grown to include quantitative behavioral analyses, sophisticated perturbations of neuronal …

The connectome of an insect brain

M Winding, BD Pedigo, CL Barnes, HG Patsolic, Y Park… - Science, 2023 - science.org
Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …

Functional Imaging and Optogenetics in Drosophila

JH Simpson, LL Looger - Genetics, 2018 - academic.oup.com
Understanding how activity patterns in specific neural circuits coordinate an animal's
behavior remains a key area of neuroscience research. Genetic tools and a brain of …

[HTML][HTML] A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection

BK Hulse, H Haberkern, R Franconville… - Elife, 2021 - elifesciences.org
Flexible behaviors over long timescales are thought to engage recurrent neural networks in
deep brain regions, which are experimentally challenging to study. In insects, recurrent …

The functional organization of descending sensory-motor pathways in Drosophila

S Namiki, MH Dickinson, AM Wong, W Korff, GM Card - Elife, 2018 - elifesciences.org
In most animals, the brain controls the body via a set of descending neurons (DNs) that
traverse the neck. DN activity activates, maintains or modulates locomotion and other …

Transforming descending input into behavior: The organization of premotor circuits in the Drosophila Male Adult Nerve Cord connectome

HSJ Cheong, K Eichler, T Stürner, SK Asinof… - bioRxiv, 2023 - biorxiv.org
In most animals, a relatively small number of descending neurons (DNs) connect higher
brain centers in the animal's head to circuits and motor neurons (MNs) in the nerve cord of …

Descending neuron population dynamics during odor-evoked and spontaneous limb-dependent behaviors

F Aymanns, CL Chen, P Ramdya - Elife, 2022 - elifesciences.org
Deciphering how the brain regulates motor circuits to control complex behaviors is an
important, long-standing challenge in neuroscience. In the fly, Drosophila melanogaster, this …

Descending control and regulation of spontaneous flight turns in Drosophila

IG Ros, JJ Omoto, MH Dickinson - Current Biology, 2024 - cell.com
The clumped distribution of resources in the world has influenced the pattern of foraging
behavior since the origins of locomotion, selecting for a common search motif in which …

Finding the gap: neuromorphic motion-vision in dense environments

T Schoepe, E Janotte, MB Milde, OJN Bertrand… - Nature …, 2024 - nature.com
Animals have evolved mechanisms to travel safely and efficiently within different habitats.
On a journey in dense terrains animals avoid collisions and cross narrow passages while …

Encoding and control of orientation to airflow by a set of Drosophila fan-shaped body neurons

TA Currier, AMM Matheson, KI Nagel - Elife, 2020 - elifesciences.org
The insect central complex (CX) is thought to underlie goal-oriented navigation but its
functional organization is not fully understood. We recorded from genetically-identified CX …