This paper reviews the recent literature on technologies and methodologies for quantitative
human gait analysis in the context of neurodegenerative diseases. The use of technological …

Physical mobility is essential to health, and patients often rate it as a high-priority clinical
outcome. Digital mobility outcomes (DMOs), such as real-world gait speed or step count …

Gait analysis, a way of assessing the manner of walking, is considered a significant criterion
in diagnosing movement disorders. Various factors contribute to the alterations in gait …

Background It is not clear how specific gait measures reflect disease severity across the
disease spectrum in Parkinson's disease (PD). Objective To identify the gait and mobility …

Introduction Although clinician-based assessment through standardized clinical rating
scales is currently the gold standard for quantifying motor impairment in Parkinson's disease …

Background Rescue of mitochondrial function is a promising neuroprotective strategy for
Parkinson's disease (PD). Ursodeoxycholic acid (UDCA) has shown considerable promise …

Peripheral neuropathy is a common problem in patients with Parkinson's disease.
Peripheral neuropathy's prevalence in Parkinson's disease varies between 4.8–55 …

Objective: Gait may be a useful biomarker that can be objectively measured with wearable
technology to classify Parkinson's disease (PD). This study aims to:(i) comprehensively …

Background: Gait disturbance is an early, cardinal feature of Parkinson's disease (PD)
associated with falls and reduced physical activity. Progression of gait impairment in …

Background Gait symptoms and balance impairment are characteristic indicators for the
progression in Parkinson's disease (PD). Current gait assessments mostly focus on straight …