[HTML][HTML] MHCII-peptide presentation: an assessment of the state-of-the-art prediction methods

Y Yang, Z Wei, G Cia, X Song, F Pucci… - Frontiers in …, 2024 - frontiersin.org
Major histocompatibility complex Class II (MHCII) proteins initiate and regulate immune
responses by presentation of antigenic peptides to CD4+ T-cells and self-restriction. The …

Organoids in gastrointestinal diseases: from bench to clinic

Q Wang, F Guo, Q Zhang, TT Hu, YT Jin, Y Yang… - MedComm, 2024 - Wiley Online Library
The etiology of gastrointestinal (GI) diseases is intricate and multifactorial, encompassing
complex interactions between genetic predisposition and gut microbiota. The cell fate …

HLA-DPA1* 02: 01~ B1* 01: 01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells

BF Zecher, D Ellinghaus, S Schloer, A Niehrs… - Gut, 2024 - gut.bmj.com
Objective Primary sclerosing cholangitis (PSC) is characterised by bile duct strictures and
progressive liver disease, eventually requiring liver transplantation. Although the …

[HTML][HTML] NKp44/HLA-DP-dependent regulation of CD8 effector T cells by NK cells

B Padoan, C Casar, J Krause, C Schultheiss… - Cell reports, 2024 - cell.com
Although natural killer (NK) cells are recognized for their modulation of immune responses,
the mechanisms by which human NK cells mediate immune regulation are unclear. Here …

Study on the Protective Effect and Mechanism of Umbilicaria esculenta Polysaccharide in DSS-Induced Mice Colitis and Secondary Liver Injury

Q Wang, Y Liu, L Gao, L Zhang… - Journal of Agricultural and …, 2024 - ACS Publications
This study aimed to explore the ameliorative effects and potential mechanisms of
Huangshan Umbilicaria esculenta polysaccharide (UEP) in dextran sulfate sodium-induced …