Mechanism and regulation of centriole and cilium biogenesis
DK Breslow, AJ Holland - Annual review of biochemistry, 2019 - annualreviews.org
The centriole is an ancient microtubule-based organelle with a conserved nine-fold
symmetry. Centrioles form the core of centrosomes, which organize the interphase …
symmetry. Centrioles form the core of centrosomes, which organize the interphase …
Microtubule organization, dynamics and functions in differentiated cells
A Muroyama, T Lechler - Development, 2017 - journals.biologists.com
Over the past several decades, numerous studies have greatly expanded our knowledge
about how microtubule organization and dynamics are controlled in cultured cells in vitro …
about how microtubule organization and dynamics are controlled in cultured cells in vitro …
Organization and function of non-dynamic biomolecular condensates
Cells compartmentalize biochemical reactions using organelles. Organelles can be either
membrane-bound compartments or supramolecular assemblies of protein and ribonucleic …
membrane-bound compartments or supramolecular assemblies of protein and ribonucleic …
The mechanism of acentrosomal spindle assembly in human oocytes
T Wu, J Dong, J Fu, Y Kuang, B Chen, H Gu, Y Luo… - Science, 2022 - science.org
Meiotic spindle assembly ensures proper chromosome segregation in oocytes. However,
the mechanisms behind spindle assembly in human oocytes remain largely unknown. We …
the mechanisms behind spindle assembly in human oocytes remain largely unknown. We …
Aurora-PLK1 cascades as key signaling modules in the regulation of mitosis
V Joukov, A De Nicolo - Science signaling, 2018 - science.org
Mitosis is controlled by reversible protein phosphorylation involving specific kinases and
phosphatases. A handful of major mitotic protein kinases, such as the cyclin B–CDK1 …
phosphatases. A handful of major mitotic protein kinases, such as the cyclin B–CDK1 …
Meiotic spindle assembly and chromosome segregation in oocytes
I Bennabi, ME Terret, MH Verlhac - Journal of Cell Biology, 2016 - rupress.org
Oocytes accumulate maternal stores (proteins, mRNAs, metabolites, etc.) during their growth
in the ovary to support development after fertilization. To preserve this cytoplasmic maternal …
in the ovary to support development after fertilization. To preserve this cytoplasmic maternal …
[HTML][HTML] A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
Primary cilia organize Hedgehog signaling and shape embryonic development, and their
dysregulation is the unifying cause of ciliopathies. We conducted a functional genomic …
dysregulation is the unifying cause of ciliopathies. We conducted a functional genomic …
A genetic basis for facultative parthenogenesis in Drosophila
Facultative parthenogenesis enables sexually reproducing organisms to switch between
sexual and asexual parthenogenetic reproduction. To gain insights into this phenomenon …
sexual and asexual parthenogenetic reproduction. To gain insights into this phenomenon …
Assembly and positioning of the oocyte meiotic spindle
B Mogessie, K Scheffler, M Schuh - Annual review of cell and …, 2018 - annualreviews.org
Fertilizable eggs develop from diploid precursor cells termed oocytes. Once every menstrual
cycle, an oocyte matures into a fertilizable egg in the ovary. To this end, the oocyte …
cycle, an oocyte matures into a fertilizable egg in the ovary. To this end, the oocyte …
The centrosome and the primary cilium: the yin and yang of a hybrid organelle
V Joukov, A De Nicolo - Cells, 2019 - mdpi.com
Centrosomes and primary cilia are usually considered as distinct organelles, although both
are assembled with the same evolutionary conserved, microtubule-based templates, the …
are assembled with the same evolutionary conserved, microtubule-based templates, the …