Complex regional pain syndrome: a recent update
Complex regional pain syndrome (CRPS) is a debilitating condition affecting the limbs that
can be induced by surgery or trauma. This condition can complicate recovery and impair …
can be induced by surgery or trauma. This condition can complicate recovery and impair …
An overview of the cannabinoid type 2 receptor system and its therapeutic potential
B Bie, J Wu, JF Foss, M Naguib - Current Opinion in …, 2018 - journals.lww.com
An overview of the cannabinoid type 2 receptor system and it... : Current Opinion in
Anesthesiology An overview of the cannabinoid type 2 receptor system and its therapeutic …
Anesthesiology An overview of the cannabinoid type 2 receptor system and its therapeutic …
The cannabinoid system and microglia in health and disease
SS Duffy, JP Hayes, NT Fiore, G Moalem-Taylor - Neuropharmacology, 2021 - Elsevier
Recent years have yielded significant advances in our understanding of microglia, the
immune cells of the central nervous system (CNS). Microglia are key players in CNS …
immune cells of the central nervous system (CNS). Microglia are key players in CNS …
Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference
QR Liu, A Canseco-Alba, HY Zhang, P Tagliaferro… - Scientific reports, 2017 - nature.com
Abstract Cannabinoid CB2 receptors (CB2Rs) are expressed in mouse brain dopamine (DA)
neurons and are involved in several DA-related disorders. However, the cell type-specific …
neurons and are involved in several DA-related disorders. However, the cell type-specific …
CB2 receptor in the CNS: From immune and neuronal modulation to behavior
W Grabon, S Rheims, J Smith, J Bodennec… - Neuroscience & …, 2023 - Elsevier
Despite low levels of cannabinoid receptor type 2 (CB2R) expression in the central nervous
system in human and rodents, a growing body of evidence shows CB2R involvement in …
system in human and rodents, a growing body of evidence shows CB2R involvement in …
The endocannabinoidome in neuropsychiatry: Opportunities and potential risks
G Morris, K Walder, S Kloiber, P Amminger… - Pharmacological …, 2021 - Elsevier
The endocannabinoid system (ECS) comprises two cognate endocannabinoid receptors
referred to as CB1R and CB2R. ECS dysregulation is apparent in neurodegenerative/neuro …
referred to as CB1R and CB2R. ECS dysregulation is apparent in neurodegenerative/neuro …
[HTML][HTML] Cannabinoid type 2 receptor system modulates paclitaxel-induced microglial dysregulation and central sensitization in rats
J Wu, M Hocevar, B Bie, JF Foss, M Naguib - The Journal of Pain, 2019 - Elsevier
Paclitaxel induces microglial activation and production of proinflammatory mediators in the
dorsal horn, which contribute to the development and maintenance of central sensitization …
dorsal horn, which contribute to the development and maintenance of central sensitization …
Targeting peripherally restricted cannabinoid receptor 1, cannabinoid receptor 2, and endocannabinoid-degrading enzymes for the treatment of neuropathic pain …
MZ Hossain, H Ando, S Unno, J Kitagawa - International journal of …, 2020 - mdpi.com
Neuropathic pain conditions including neuropathic orofacial pain (NOP) are difficult to treat.
Contemporary therapeutic agents for neuropathic pain are often ineffective in relieving pain …
Contemporary therapeutic agents for neuropathic pain are often ineffective in relieving pain …
Biased agonism at the cannabinoid receptors–evidence from synthetic cannabinoid receptor agonists
The type 1 and type 2 cannabinoid receptors are G protein-coupled receptors implicated in a
variety of physiological processes and diseases. Synthetic cannabinoid receptor agonists …
variety of physiological processes and diseases. Synthetic cannabinoid receptor agonists …
The role of neuroinflammation in complex regional pain syndrome: a comprehensive review
Abstract Complex Regional Pain Syndrome (CRPS) is an excess and/or prolonged pain and
inflammation condition that follows an injury to a limb. The pathogenesis of CRPS is …
inflammation condition that follows an injury to a limb. The pathogenesis of CRPS is …