[HTML][HTML] 3D bioprinting photo-crosslinkable hydrogels for bone and cartilage repair
Q Mei, J Rao, HP Bei, Y Liu, X Zhao - International journal of …, 2021 - ncbi.nlm.nih.gov
Abstract Three-dimensional (3D) bioprinting has become a promising strategy for bone
manufacturing, with excellent control over geometry and microarchitectures of the scaffolds …
manufacturing, with excellent control over geometry and microarchitectures of the scaffolds …
[HTML][HTML] Bisphosphonate conjugation for bone specific drug targeting
KB Farrell, A Karpeisky, DH Thamm, S Zinnen - Bone reports, 2018 - Elsevier
Bones provide essential functions and are sites of unique biochemistry and specialized
cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has …
cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has …
Remarkable potential of the α-aminophosphonate/phosphinate structural motif in medicinal chemistry
R-Aminophosphonic acids are broadly defined as analogues of amino acids in which the
carboxylic group is replaced by a phosphonic acid or related group (usually phosphonous or …
carboxylic group is replaced by a phosphonic acid or related group (usually phosphonous or …
Targeted delivery to bone and mineral deposits using bisphosphonate ligands
LE Cole, T Vargo-Gogola, RK Roeder - Advanced drug delivery reviews, 2016 - Elsevier
The high concentration of mineral present in bone and pathological calcifications is unique
compared with all other tissues and thus provides opportunity for targeted delivery of …
compared with all other tissues and thus provides opportunity for targeted delivery of …
Targeting polymer therapeutics to bone
An aging population in the developing world has led to an increase in musculoskeletal
diseases such as osteoporosis and bone metastases. Left untreated many bone diseases …
diseases such as osteoporosis and bone metastases. Left untreated many bone diseases …
The role of sphingosine-1-phosphate in bone remodeling and osteoporosis
Osteoporosis is a systemic bone disease that affects more than 200 million people
worldwide and is caused by the disruption of the equilibrium between osteoclastic bone …
worldwide and is caused by the disruption of the equilibrium between osteoclastic bone …
Recent advances in bone-targeted therapy
C Shi, T Wu, Y He, Y Zhang, D Fu - Pharmacology & therapeutics, 2020 - Elsevier
The coordination between bone resorption and bone formation plays an essential role in
keeping the mass and microstructure integrity of the bone in a steady state. However, this …
keeping the mass and microstructure integrity of the bone in a steady state. However, this …
Alendronate/folic acid-decorated polymeric nanoparticles for hierarchically targetable chemotherapy against bone metastatic breast cancer
SH Chen, TI Liu, CL Chuang, HH Chen… - Journal of Materials …, 2020 - pubs.rsc.org
To considerably enhance treatment efficacy for bone metastatic breast cancer via dual
bone/tumor-targeted chemotherapy, a nanoparticle-based delivery system comprising poly …
bone/tumor-targeted chemotherapy, a nanoparticle-based delivery system comprising poly …
Doxorubicin-poly (ethylene glycol)-alendronate self-assembled micelles for targeted therapy of bone metastatic cancer
W Ye, Y Zhao, H Li, R Na, F Li, Q Mei, M Zhao… - Scientific reports, 2015 - nature.com
In order to increase the therapeutic effect of doxorubicin (DOX) on bone metastases, a
multifunctional micelle was developed by combining pH-sensitive characteristics with bone …
multifunctional micelle was developed by combining pH-sensitive characteristics with bone …
Smart bioinks for the printing of human tissue models
Z Maan, NZ Masri, SM Willerth - Biomolecules, 2022 - mdpi.com
3D bioprinting has tremendous potential to revolutionize the field of regenerative medicine
by automating the process of tissue engineering. A significant number of new and advanced …
by automating the process of tissue engineering. A significant number of new and advanced …