[HTML][HTML] Lipid systems for the delivery of amphotericin B in antifungal therapy
C Faustino, L Pinheiro - Pharmaceutics, 2020 - mdpi.com
Amphotericin B (AmB), a broad-spectrum polyene antibiotic in the clinic for more than fifty
years, remains the gold standard in the treatment of life-threatening invasive fungal …
years, remains the gold standard in the treatment of life-threatening invasive fungal …
Nano-and micro-based inhaled drug delivery systems for targeting alveolar macrophages
Introduction: Macrophages are the most versatile cells in the hematopoietic system and are
strategically distributed in tissues to fight pathogens or other foreign particles. In the lung …
strategically distributed in tissues to fight pathogens or other foreign particles. In the lung …
Bile salts-containing vesicles: promising pharmaceutical carriers for oral delivery of poorly water-soluble drugs and peptide/protein-based therapeutics or vaccines
MH Aburahma - Drug delivery, 2016 - Taylor & Francis
Most of the new drugs, biological therapeutics (proteins/peptides) and vaccines have poor
performance after oral administration due to poor solubility or degradation in the …
performance after oral administration due to poor solubility or degradation in the …
An effective strategy to develop potent and selective antifungal agents from cell penetrating peptides in tackling drug-resistant invasive fungal infections
The high mortality rate of invasive fungal infections and quick emergence of drug-resistant
fungal pathogens urgently call for potent antifungal agents. Inspired by the cell penetrating …
fungal pathogens urgently call for potent antifungal agents. Inspired by the cell penetrating …
Antifungal therapy for systemic mycosis and the nanobiotechnology era: improving efficacy, biodistribution and toxicity
Fungal diseases have been emerging as an important public health problem worldwide with
the increase in host predisposition factors due to immunological dysregulations …
the increase in host predisposition factors due to immunological dysregulations …
Lipid-based pulmonary delivery system: a review and future considerations of formulation strategies and limitations
CL Ngan, AA Asmawi - Drug delivery and translational research, 2018 - Springer
Inhalation therapy of lipid-based carriers has great potential in direct target towards the root
of respiratory diseases, which make them superior over other drug deliveries. With the …
of respiratory diseases, which make them superior over other drug deliveries. With the …
Multiple nanoemulsion system for an oral combinational delivery of oxaliplatin and 5-fluorouracil: preparation and in vivo evaluation
R Pangeni, SW Choi, OC Jeon, Y Byun… - International journal of …, 2016 - Taylor & Francis
Oxaliplatin (OXA) is a third-generation cisplatin analog that has been approved as first-line
chemotherapy in combination with 5-fluorouracil (5-FU) for the treatment of resectable and …
chemotherapy in combination with 5-fluorouracil (5-FU) for the treatment of resectable and …
Effect of Amphotericin B on the thermodynamic stability, aggregation state, hemolysis and antifungal activity of Amphotericin B-nonionic surfactant micellar system
L Liu, Z Liang, Y Zhou, H Pan, H Liu - Journal of Molecular Liquids, 2023 - Elsevier
Amphotericin B (AmB) is a toxic and low solubility antifungal drug. In this paper, AmB was
encapsulated by different nonionic surfactants and the effect of their structures on AmB was …
encapsulated by different nonionic surfactants and the effect of their structures on AmB was …
Preparation, characterization, and evaluation of amphotericin B-loaded MPEG-PCL-g-PEI micelles for local treatment of oral Candida albicans
L Zhou, P Zhang, Z Chen, S Cai, T Jing… - International journal …, 2017 - Taylor & Francis
Fatal Candida albicans infections in the mucosal system can occur in association with
immune-compromised diseases and dysbacteriosis. Currently, amphotericin B (AmB) is …
immune-compromised diseases and dysbacteriosis. Currently, amphotericin B (AmB) is …
Modulating tumor immunity by metronomic dosing of oxaliplatin incorporated in multiple oral nanoemulsion
In this study, a system for oral delivery of oxaliplatin (OXA) was prepared for metronomic
chemotherapy to enhance antitumor efficacy and modulate tumor immunity. OXA was …
chemotherapy to enhance antitumor efficacy and modulate tumor immunity. OXA was …