Mitochondrial dysfunction as a signaling target for therapeutic intervention in major neurodegenerative disease

SV Mangrulkar, NL Wankhede, MB Kale… - Neurotoxicity …, 2023 - Springer
Neurodegenerative diseases (NDD) are incurable and the most prevalent cognitive and
motor disorders of elderly. Mitochondria are essential for a wide range of cellular processes …

[HTML][HTML] Boosting mitochondrial health to counteract neurodegeneration

J Burtscher, M Romani, G Bernardo, T Popa… - Progress in …, 2022 - Elsevier
Mitochondrial health is based on a delicate balance of specific mitochondrial functions (eg
metabolism, signaling, dynamics) that are impaired in neurodegenerative diseases …

Using a Caenorhabditis elegans Parkinson's Disease Model to Assess Disease Progression and Therapy Efficiency

S Hughes, M van Dop, N Kolsters, D van de Klashorst… - Pharmaceuticals, 2022 - mdpi.com
Despite Parkinson's Disease (PD) being the second most common neurodegenerative
disease, treatment options are limited. Consequently, there is an urgent need to identify and …

Acoustic streaming enabled moderate swimming exercise reduces neurodegeneration in C. elegans

J Bhadra, N Sridhar, AK Fajrial, N Hammond, D Xue… - Science …, 2023 - science.org
Regular physical exercise has been shown to delay and alleviate neurodegenerative
diseases. Yet, optimum physical exercise conditions that provide neuronal protection and …

Caenorhabditis elegans as a model system to evaluate neuroprotective potential of nano formulations

P Chauhan, K Wadhwa, G Singh - Frontiers in Nanotechnology, 2022 - frontiersin.org
The impact of neurodegenerative illnesses on society is significant, but the mechanisms
leading to neuronal malfunction and death in these conditions remain largely unknown …

Synthesis and Physicochemical Stability of a Copaiba Balsam Oil (Copaifera sp.) Nanoemulsion and Prospecting of Toxicological Effects on the Nematode …

IC Bezerra, ERS Santos, JSR Bisneto, PP Perruci… - ACS …, 2024 - ACS Publications
Nanoemulsions are dispersions of oil-in-water (O/W) and water-in-oil (W/O) immiscible
liquids. Thus, our main goal was to formulate a nanoemulsion with low surfactant …

Chronic Exercise and the Treatment of Progressive Disorders

K Richardson - 2023 - search.proquest.com
Exercise is a known, beneficial treatment for a variety of normal (aging) and abnormal
(disease) declines in health. These benefits can be observed in a range of tissues, including …