Epigenetic regulation of innate immune dynamics during inflammation
BA Caldwell, L Li - Journal of leukocyte biology, 2024 - academic.oup.com
Innate immune cells play essential roles in modulating both immune defense and
inflammation by expressing a diverse array of cytokines and inflammatory mediators …
inflammation by expressing a diverse array of cytokines and inflammatory mediators …
Succinate mediates inflammation-induced adrenocortical dysfunction
The hypothalamus-pituitary-adrenal (HPA) axis is activated in response to inflammation
leading to increased production of anti-inflammatory glucocorticoids by the adrenal cortex …
leading to increased production of anti-inflammatory glucocorticoids by the adrenal cortex …
Utilizing the codon adaptation index to evaluate the susceptibility to HIV-1 and SARS-CoV-2 related coronaviruses in possible target cells in humans
H Zhou, R Ren, SST Yau - Frontiers in cellular and infection …, 2023 - frontiersin.org
Comprehensive identification of possible target cells for viruses is crucial for understanding
the pathological mechanism of virosis. The susceptibility of cells to viruses depends on …
the pathological mechanism of virosis. The susceptibility of cells to viruses depends on …
Altered DNA methylation underlies monocyte dysregulation and innate exhaustion memory in sepsis
Innate immune memory is the process by which pathogen exposure elicits cell-intrinsic
states to alter the strength of future immune challenges. Such altered memory states drive …
states to alter the strength of future immune challenges. Such altered memory states drive …
Boronic functionalized aptamer macroarrays with dual-recognition and isothermal amplification of lipopolysaccharide detection
Q Zhang, Y Wang, D Ma, X Pan, E Sheng, J Shen… - Microchimica Acta, 2024 - Springer
A highly sensitive dual-recognition fluorescence amplification method is presented for
lipopolysaccharide (LPS) detection based on boronic functionalized aptamer macroarrays …
lipopolysaccharide (LPS) detection based on boronic functionalized aptamer macroarrays …
Shock drives a highly coordinated transcriptional and DNA methylation response in the endothelium
RB Ramos, N Martino, D Chuy, S Lu… - bioRxiv, 2022 - biorxiv.org
Abstract Interleukin 6 (IL-6) is a major mediator of the cytokine storm during shock. Its actions
on the endothelium lead to pathological vascular leakage, leukocyte adhesion, and …
on the endothelium lead to pathological vascular leakage, leukocyte adhesion, and …