Clinical impact of HY alloimmunity

R Popli, B Sahaf, H Nakasone, JYY Lee… - Immunologic …, 2014 - Springer
HY antigens are a group of minor histocompatibility antigens encoded on the Y-
chromosome with homologous HX antigens on the X-chromosome. The disparate regions of …

Allogeneic HY antibodies detected 3 months after female-to-male HCT predict chronic GVHD and nonrelapse mortality in humans

H Nakasone, L Tian, B Sahaf, T Kawase… - Blood, The Journal …, 2015 - ashpublications.org
Allogeneic antibodies against minor histocompatibility antigens encoded on the Y
chromosome (HY-Abs) develop after hematopoietic cell transplant (HCT) of male recipients …

[HTML][HTML] Risks and benefits of sex-mismatched hematopoietic cell transplantation differ according to conditioning strategy

H Nakasone, M Remberger, L Tian, P Brodin… - …, 2015 - ncbi.nlm.nih.gov
Sex-mismatched hematopoietic cell transplantation is linked to increased graft-versus-host
disease and mortality in myeloablative conditioning. Here we evaluated outcomes of 1,041 …

Red blood cell transfusions are associated with HLA class I but not H‐Y alloantibodies in children with sickle cell disease

RS Nickel, JE Hendrickson, MM Yee… - British journal of …, 2015 - Wiley Online Library
Blood transfusions can induce alloantibodies to antigens on red blood cells (RBC s), white
blood cells and platelets, with these alloantibodies affecting transfusion and transplantation …

Profiling humoral immune responses to Clostridium difficile-specific antigens by protein microarray analysis

OH Negm, MR Hamed, EM Dilnot… - Clinical and Vaccine …, 2015 - Am Soc Microbiol
Clostridium difficile is an anaerobic, Gram-positive, and spore-forming bacterium that is the
leading worldwide infective cause of hospital-acquired and antibiotic-associated diarrhea …

Development of recombinant antigen array for simultaneous detection of viral antibodies

Y Liu, F Yu, H Huang, J Han - PloS one, 2013 - journals.plos.org
Protein microarrays have been developed to study antibody reactivity against a large
number of antigens, demonstrating extensive perspective for clinical application. We …

Novel microarrays for simultaneous serodiagnosis of multiple antiviral antibodies

PM Sivakumar, N Moritsugu, S Obuse, T Isoshima… - PloS one, 2013 - journals.plos.org
We developed an automated diagnostic system for the detection of virus-specific
immunoglobulin Gs (IgGs) that was based on a microarray platform. We compared efficacies …

[HTML][HTML] Presensitization to HY antigens in female donors prior to transplant is not associated with male recipient post-transplant HY antibody development nor with …

H Nakasone, B Sahaf, L Tian, T Wang… - …, 2016 - ncbi.nlm.nih.gov
It has been shown that chronic graft-versus-host disease (cGVHD) incidence is significantly
increased in male recipients receiving allogeneic hematopoietic cell transplant from female …

Excess female siblings and male fetal loss in families with systemic lupus erythematosus

R Aggarwal, AL Sestak, EF Chakravarty… - The Journal of …, 2013 - jrheum.org
Objective. Systemic lupus erythematosus (SLE) occurs more frequently among women than
men. We aimed to determine whether the male-female ratio in SLE families is different from …

A protein microarray assay for serological determination of antigen-specific antibody responses following clostridium difficile infection

OH Negm, M Hamed… - Journal of Visualized …, 2018 - pmc.ncbi.nlm.nih.gov
We provide a detailed overview of a novel high-throughput protein microarray assay for the
determination of anti-Clostridium difficile antibody levels in human sera and in separate …