Fetuin-A is a heterodimeric plasma glycoprotein containing an A-chain of 282 amino acids
and a B-chain of 27 amino acid residues linked by a single inter-disulfide bond. It is …

Patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) have
significant cardiovascular morbidity and mortality that is in part due to the development of …

Autophagy is a bulk protein degradation system that likely plays an important role in normal
proximal tubule function and recovery from acute ischemic kidney injury. Using conditional …

The final step of biomineralization is a chemical precipitation reaction that occurs
spontaneously in supersaturated or metastable salt solutions. Genetic programs direct …

High concentrations of extracellular phosphate are toxic to cells. Impaired urinary phosphate
excretion increases serum phosphate level and induces a premature-ageing phenotype …

Sixty-six years have elapsed since the discovery of fetuin in 1944, but its importance in
mammalian physiology has only recently been appreciated. Fetuin, first isolated from fetal …

Autophagy is a highly conserved bulk protein degradation pathway involved in cellular
homeostasis. Although emerging evidence indicates involvement of autophagy in various …

Cultivated meat production requires an efficient, robust and highly optimized serum-free cell
culture media for the needed upscaling of muscle cell expansion. Existing formulations of …

This article focuses on the relevance of amorphous calcium (and magnesium) phosphates in
living organisms. Although crystalline calcium phosphate (CaP)-based materials are known …

Fetuin-A is an important inhibitor of extraosseous calcification, but some of the studies that
used ELISAs did not identify a significant relationship between serum fetuin-A levels and …