The 2022 Metrics of the Human Proteome from the HUPO Human Proteome Project (HPP)
show that protein expression has now been credibly detected (neXtProt PE1 level) for 18 …

For almost nearly a century, memory functions have been attributed only to acquired
immune cells. Lately, this paradigm has been challenged by an increasing number of …

As a basic parameter of the intracellular microenvironment, viscosity is closely related to the
development of cancer. Thus, it is necessary to utilize a sensitive tool to visualize the …

MARCKS (myristoylated alanine-rich C-kinase substrate) is a membrane-associated protein
expressed in many cell types, including macrophages. MARCKS is functionally implicated in …

Despite a well-known association between gut barrier defect (leaky gut) and several
diseases, data on translocation of pathogen molecules, including bacterial DNA (blood …

Metabolic adaptations shape immune cell function. In the acute response, a metabolic
switch towards glycolysis is necessary for mounting a proinflammatory response. During the …

Because both endotoxemia and gut dysbiosis post-splenectomy might be associated with
systemic infection, the susceptibility against infection was tested by dextran sulfate solution …

Simple Summary Macrophages, depending on their phenotype, can either destroy or
stimulate cancer cells. Therefore, it is very important to identify the conditions under which …

The responses of macrophages to lipopolysaccharide (LPS) might determine the direction of
clinical manifestations of sepsis, which is the immune response against severe infection …

Dysfunction of the blood–brain barrier (BBB) is involved in the pathogenesis of many
cerebral diseases. Oxidative stress and inflammation are contributing factors for BBB injury …